on Day 28, respectively. TNSS was highly correlated within-subjects between the two NEC exposures (r50.73, p<0.0001), TOSS was not (r50.28, p>0.05). Baseline SPT to cat and IgE to cat and Fel d 1 did not correlate with magnitude of nasal or ocular symptoms (absolute value of Spearman's r<0.3, p>0.05 for all comparisons). CONCLUSIONS: Mean nasal and ocular symptoms of cat-allergic asthmatics, were reproduced in the NEC; however, individual ocular symptoms were not. NEC is a good model for development of therapies for cat-specific allergic rhinoconjunctivitis.
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