The passive circuit was shown to be as effective and safe as the active circuit during home invasive ventilation in the subjects with amyotrophic lateral sclerosis. A future randomized controlled study is necessary to confirm these results and to extend indications to other pathologies.
HighlightsPatients with chronic hypersecretion (CH) of tracheobronchial mucus are a clinical challenge. They have an impaired quality of life, frequent exacerbations, and hospitalizations with need of antibiotics and other type of expensive treatments.Chest physical therapy evolved along the last decades and new techniques are currently used to help patients clear the airways efficiently. Among these airway clearance techniques (ACTs), the use of positive expiratory pressure (PEP) is considered one of the most effective.We report the retrospective evaluation of 162 patients with CH due to chronic obstructive pulmonary disease or bronchiectasis undergoing ACT in our Pulmonary Rehabilitation Department. They were treated either with PEP or with a new PEP device called UNIKO®, which applies PEP in a temporary manner (TPEP).Comparing the two groups of patients, both treatments (i.e., PEP and TPEP) were followed by great improvements in physiological parameters of spirometry and gas exchange. However, subdividing patients, it was evident that TPEP had better effects than PEP in patients with emphysema and in patients on long-term oxygen treatment, while PEP was superior at least in some parameters in patients on mechanical ventilation.This study, albeit retrospective and calling for controlled clinical trials, suggests that different ACTs can be applied in different populations of patients.
reported general guidelines for management of daytime MPV in NMDs. This report could not present all the detail regarding the technical issues important for clinical success of MPV. Based on the expert workshop discussions and the evidence from existing studies, the current narrative review aims to identify the technical issues of MPV and offers guidance via a decisional algorithm and educational figures providing relevant information that is important for successful implementation of MPV.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.