(Kauppila et al., 1982) and thyroid hormone (Orava et al., 1983) (Fentiman et al., 1985). To extend these studies, we have investigated the effects of IFN-LU on serum testosterone levels in normal healthy men who, during the experimental period, carried out their normal activities.Two volunteers received one subcutaneous injection of 3 X 106 IU of partially purijied human IFN-a (P-IFA) (Cantell and Hirvonen, 1977) with a specijic activity of 0.9 X lo6 I U h g protein, followed by 1.5 X 106 IU on
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