Left‐handed metamaterials (LHMs) composed of random dendritic cells demonstrate a multi‐band resonance and negative refractive index. A nano‐assembly approach is established to fabricate optical LHMs. Random nanostructures of silver dendritic cells are prepared and further fabricated into a sandwich‐like structure with a dielectric medium. The dentritic nano‐assembled configuration reveals a multi‐band resonance and a high intensity of the pass‐band at infrared frequencies, and can be facilely and cheaply prepared on a large‐scale of effective area.

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Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors in China. However, there are no targets to treat ESCC because the molecular mechanism behind the cancer is still unclear. Here, we found a novel long noncoding RNA LINC02820 was upregulated in ESCC and associated with the ESCC clinicopathological stage. Through a series of functional experiments, we observed that LINC02820 only promoted the migration and invasion capabilities of ESCC cell lines. Mechanically, we found that LINC02820 may affect the cytoskeletal remodeling, interact with splice factor 3B subunit 3 (SF3B3), and cooperate with TNFα to amplify the NF-κB signaling pathway, which can lead to ESCC metastasis. Overall, our findings revealed that LINC02820 is a potential biomarker and therapeutic target for the diagnosis and treatment of ESCC.

Optical metamaterials (OMs) at visible wavelengths have been extensively developed. OMs reported recently are all composed of periodic structure, and fabricated by top-down approaches. Here demonstrated are the colored visible light frequency metamaterials composed of double layer array disordered and geometrical variational dendritic cells as well as fabricated by a novel bottom-up approach. The experiment demonstrates that the OMs composed of random silver dendritic cells which caused the appearance of multiple transmission passbands at red and yellow light frequencies.Moreover, the slab focusing experiment reveals a clear point image in the range of half-wavelength with an intensity of 5% higher than that of the light source. The colored OMs proposed will create a new way to prepare the cloak and the perfect lens suitable for optical frequency.