Background: The field of soft tissue tumors is vast and yet to be explored. The diagnosis of these tumors is always challenging for the pathologists. The overlap in the clinical and radiological features makes histopathology very crucial in their identification.
Methods: This is a retrospective study of soft tissue tumors over a period of 18 months from January 2014 to June 2015 conducted in the Department of Pathology. The gross specimens were fixed in 10% formalin and the slides were stained by Hematoxylin and Eosin. Immunohistochemistry was performed wherever necessary.
Result: A total of 235 soft tissue tumors were studied of which benign cases were 225 (95.75%), intermediate 04 (1.70%) and malignant 06 (2.55%). The tumors had a male preponderance, with majority in the third decade, predominantly occurring in the head neck region. Of a total of eleven categories of soft tissue tumors in our study, the adipocytic category was the most common followed by the nerve sheath and vascular tumors.
Conclusion: Molecular diagnosis have started to gain momentum in the field of soft tissue tumors, however histomorphology still remains the gold standard.
Hidradenomas are the benign cutaneous tumors of sweat gland origin, with the clear cell type constituting the most frequent histologic variety. Usually, they are diagnosed in the elderly population, the peak incidence being the fifth to sixth decade. Very few cases of hidradenoma have been documented in children in their first decade of life. Here, we present a rare and interesting case of a 10-year-old boy who presented with swelling on the anterior aspect of the neck, since birth. The histological findings were consistent with the diagnosis of nodular hidradenoma.
Background: Fine needle aspiration cytology (FNAC) of suspected salivary gland lesions has an established role in preoperative diagnosis and management of patients. However diverse morphological patterns and overlapping features make it a challenging job, to give a precise diagnosis at times.Methods: This was a prospective study done from October 2011 to October 2013. Fine needle aspiration cytology was performed in 64 patients with clinically significant salivary gland lesions.Results: Fine needle aspiration cytology categorized 38 (59.4%) of the salivary gland lesions as neoplastic and 26 (40.6 %) as non- neoplastic lesions. Amongst the neoplastic lesions, 86.9% were benign and 13.2% were malignant cases.Conclusions: FNAC of the salivary gland is simple, cheap, safe and reliable technique in the primary diagnosis of salivary gland lesions.
Fungal infections of the gastrointestinal tract (GIT) are not rare, but get missed due to their misleading clinical features. Here we report three GIT fungal infections at different locations with varied symptoms. We received surgical resection specimens with the clinical suspicion of malignancy for all. The first was a case of Aspergillosis, at an uncommon site, esophageal, in a 60year diabetic male with a suspicion of carcinoma in view of presence of dysphagia and a stricture on CT. The second was a 60-year male, a case of stomach Zygomycosis with no definite immunosuppression, who presented with an intra-operative suspicion of malignancy, and showed fungal angio-invasion and ischemic perforation. Third was a 32year immunocompetent male, a case of GI histoplasmosis with an uncommon presentation, showing obstructive symptoms due to an ileocaecal mass with a clinical suspicion of TB/malignancy. Thus, a high index of suspicion for fungal a etiology in GIT is essential, because misdiagnosis can lead to a radical surgery. Timely treatment with appropriate antifungal therapy is crucial as high mortality is associated with certain fungi.
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