Lupus nephritis is an autoimmune disease caused by systemic lupus erythematous, the prevalence of SLE and the chances of developing lupus nephritis (LN) vary considerably between different regions of the world and different races and ethnicities, a number of factors like genetic, environmental and immunology lead to inflammation of kidneys which is identified by biopsy, it is classified into six types based on the level of tissue damage and it is treated by induction, maintenance, adjuvant therapy and biological therapy. Mostly immunosuppressant's, antimalarials are used.
Background: Hypertension represents the major health problem primarily because of its role in contributing to the initiation and progression of major cardiovascular diseases. The aim of the present study was to determine the existing practice of prescribing pattern of Anti Hypertensive medication in tertiary care hospital in prospective of standard treatment of guidelines. Methods and materials:A hospital based prospective observational study on Anti Hypertensive agent prescriptions was carried out among patients who were above 20 years of age and Inpatients in the tertiary care corporate hospital. The total of 270 prescriptions of patients suffering from hypertension were included. The collected data were sorted and analyzed on the basis of demographic characteristics and co-morbidities. Results:It was a prospective observational study in which 270 patients were selected. The most commonly prescribed Antihypertensive drugs in our study was telmisartan and least prescribed was spironolactone, diltiazem and indapamide. The drugs were prescribed as mono therapy, dual therapy, triple therapy and poly therapy. Mono therapy of about (51%) was most frequently prescribed and Poly therapy was least prescribed of about (7%). Conclusion:The study revealed that the prevalence of hypertension was predominantly more in male patients than in female patients. Present study represents the current prescribing trend of antihypertensive agents. Angiotensin receptor blockers were the most frequently prescribed class of drug in monotherapy.
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