Background: Diabetes mellitus is a major health issue that is one of the leading causes of cardiovascular disease. Recent studies have found a link between uncontrolled diabetes and cardiovascular disease, with dyslipidaemia predicting glycated-hemoglobin (HbA1c), which could be a major contributor to type 2 diabetes complications and etiology. Objectives: The objective of present study was estimate lipid profiles among control and uncontrolled type 2 diabetic patients. Subjects and Methods: Analytical case control based study, One hundred twenty participate were included in study, 70 patients with DM as case group refer to Abuagala Center and difference follow up diabetic center and 50 non diabetic subjects taken as control group males and females their age between 20 to 80 years. Fasting blood glucose (FBG), blood HbA1c, and serum lipid parameters were measured by CobseC311 from Roche instrument. Data was analyzed using SPSS version 22, which expressed as (mean±SD) with p.value. Result:Among120 participant the levels of fasting blood glucose,blood HbA1c,and Triglyceridewereincreased significantly in T2DM (161.7±72.5mg/dl), (8.88±3.9 %), (121±61.9 mg/dl)when compare with control group(91.28±13.9), (5.7±0.50), (80±11.7) with P.value (0.000),while total Cholesterol, High Density Lipoprotein, and Low Density Lipoprotein were not significant different in T2DM when compared with control group. There was weak positive correlation between HbA1c with FBG, CHOL, LDL, and HDL (r = 0.207, P =0.089, r = 0.186, P =0.124, r = 0.167, P =0.168, r = 0.308, P =0.01) respectively, while TG hadweak negative correlation (r =- 0.146, P =0.228). Conclusion: The results indicated to considerable increase in the lipid profile levels in type two diabetic patients when compared with healthy controls group which may lead to increase in coronary risk factors.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.