In this paper, an efficient plasma jet array based on the E × B enhancement was developed. The direction of the magnetic field was the same as the propagation direction of the plasma jet, and the direction of the electric field was perpendicular to the plasma jet. The E × B enhancement increased the length of the plasma jet from 0.5 to 1.8 cm, the discharge current peak by 37.8%, and the plasma power by 11.1%, compared with the control case. Three‐dimensional simulation of electrons movement indicates that the confinement of electrons in the high argon concentration region was the main reason for the E × B enhancement. The stronger discharge based on the E × B enhancement increased the ion density in the open air significantly. The charged aerosols were generated through the diffusion charging mechanism. The image charge electric force between charged and neutral aerosols increased the collision rate between aerosols, therefore, the larger aerosols were generated, and 108% more deposition of aerosols than the natural settlement case were achieved.
Improving the transdermal delivery efficiency of medicine is a crucial measure to improve the treatment efficiency of psoriasis. This paper developed a low-cost, highly active, and large-action-area low-temperature plasma (LTP) jet array. The two components of plasma—the high concentration of reactive oxygen and nitrogen species and the strong electric field—easily changed the structural integrity of the stratum corneum, which enhanced the transdermal delivery of the medicine. Tripterygium wilfordii Hook F (TwHF) is a medicine used to treat autoimmune and inflammatory conditions. The enhanced transdermal delivery of TwHF significantly alleviated the severed psoriasiform dermatitis induced by the imiquimod. Unlike the TwHF treatment alone, the LTP + TwHF treatment was more efficient at suppressing epidermal thickening and inhibiting systemic inflammation without noticeable side effects. LTP + TwHF treatment provides a potential new solution for psoriasis treatment.
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