Background and Objective: Intra-articular magnesium sulfate, an N-methyl-d-aspartate receptor blocker, would be of particular interest in either producing post-operative analgesia or enhancing the analgesic effect of intraarticular bupivacaine. This study was aimed to investigate the efficacy of intra-articular magnesium sulfate injection as post-operative analgesic agent knee arthroscopy. A decrease in visual analog scale (VAS) score followed by a decrease in analgesic requirement and subsequently less analgesic requirement. Materials and Methods: This is a randomized, prospective, double-blinded clinical trial conducted on patients undergoing arthroscopic partial meniscectomy referred to Ahvaz Razi Hospital, Iran. 94 patients were randomly divided into two parallel groups. The saline placebo group received 20 ml of isotonic saline, and the magnesium sulfate group received 20 ml of isotonic saline containing 1 g magnesium sulfate. The post-operative analgesia was assessed using VAS recorded at 5, 60, 120, and 240 min post-surgery. Patients were evaluated at rest and under movement. Results: The magnesium sulfate group showed a significant reduction in VAS score, a significantly increased time to first post-operative analgesic request, as well as significantly reduced total analgesic requirement than the control group. Conclusion: Magnesium sulfate produces a reduction in post-operative pain when given intra-articularly in comparison to saline placebo.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.