Human Papilloma Virus (HPV) related verrucae pedis persist, seemingly evading host immune surveillance, yet sometimes disappear with inflammation. The absence, or reduction, of a cellular immune response may explain why verrucae treatments are not uniformly successful and treatment can be difficult even in immune-competent individuals. Little investigation has been undertaken into the potential benefit and efficacy of needling verrucae, a treatment modality causing HPV infected keratinocyte destruction in addition to inducing an assumed enhanced immune response. A review of clinical practice is presented, reporting the treatment method and results of data collected from a retrospective review of 45 patients. Thirty-one (69%) cases demonstrated complete resolution of verrucae following needling treatment. Three patients demonstrated reduction in size and pain whilst 11 showed no improvement. No adverse events were noted. Needling may have a place in the management of verrucae pedis in an adult population but a large scale study utilising objective measures and a control intervention would provide more detailed efficacy data along with a greater understanding of the effects of this treatment on long term immunity.
perform a-ersion, tlius overcoming tlle miiuscular spasm .ndl relaxinig the perineum. Professor Blair Bell has been in the lhabit for miiany years now of measurinlg the transverse diameter of the pelvic outlet in cases requiring the repair of complete lacerations of the perineum; he hias constantly founid this to be so iiarrowed that the head must have beien forced further lack than niormal in the process of delivery, and the perineum inevitably and completely lacerated.-I am, etc., Liverpool, Nov. 29th. M. M. DATNOW.
OBITUAhY. L[VLAJzo 833 coverable this must be in the vast majority of cases rejected. How is 'it possible seriously to discuss tuch a c1u8e when others-gross, palpable, and sufficient-tbrust themselves into the view of the most superficial observer ?-I am, etc.,
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.