Natural gas has become a global commodity in the energy consumption. New technologies, like as gas-to-liquid conversion technology, contribute to this. But more than 16% of the currently known global gas reserves cannot be produced, because they are heavily contaminated by CO 2 and/or H 2 S: (CO 2 > 10% and H 2 S > 5%). The traditional technology of amine treatment is not capable to economically remove these contaminants. The objective of this article is to investigate the possibilities of centrifugal separation in a way to resolve the existing problem. After analyzing the existing situation, in the centrifugal separation of natural gas, some innovations in separators' design and theory are suggested. The aim of the presented theoretical considerations is that the complex theory of separation should be adjusted to the needs of engineers engaged in design, development and operation of these devices.