It has been suggested previously that copper transport in Escherichia coli is mediated by the products of at least six genes, cutA, cutB, cutC, cutD, cutE, and cutF. A mutation in one or more of these genes results in an increased copper sensitivity ( Copper is an essential heavy metal trace element, which plays a vital role in the growth and physiology of aerobic organisms; however, excess of this metal results in cell death.
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