The article presents the results of research of cytokines (- and -interferons and tumor necrosis factor-а) and monoamines (adrenalin, noradrenalin, dopamin, serotonin) in blood and cerebrospinal fluid in 151 patients with multiple sclerosis. The correlation between immune, biochemical changes and clinical activity and course of disease were revealed. The immunocorrection with -interferon is recommended.
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