This report details the diagnosis of Jeryl-Lynn vaccine-derived parotitis in a medical student after receiving the measles-mumps-rubella vaccine. Diagnostic verification of mumps vaccine-induced disease was a priority given a recent mumps outbreak affecting 13 students in the undergraduate university and another medical student at the same university's affiliated medical school. Ultimately, genotypic analysis of the medical student's buccal mumps polymerase chain reaction sample confirmed vaccine-induced disease.
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