The potential dermal and respiratory exposure assessment and risk assessment for applicator were performed with cypermethrin EC. The pesticide was applied on a mandarin field using a power sprayer. Gloves were used for the hand exposure assessment, mask for face, and dermal patches for the other parts of the body. Personal air monitor equipped with a XAD-2 resin was used for the respiratory exposure assessment. During the application of cypermethrin in the field, the rate of potential dermal exposure ranged from 28.1 to 58.8 mg/h. The major exposure parts were upper-arms (22.1-24.6%) and legs (thigh and shin, 28.3-29.2%) for females and thigh (21.0-46.9%) and hand (14.9-19.3%) for males. Females were exposed more than males. No exposure was detected from the respiratory monitoring. For risk assessment, the potential dermal exposure (PDE), the absorbable quantity of exposure (AQE), and the margin of safety (MOS) were calculated. Among those four risk assessments, MOS was < 1 in only trial I, which indicated any possibility of risk. However, in the others, the possibility of risk was little. Moreover, the safe work time ranged from 3.61 h to 9.69 h.

Based on the proposal that the Skyrme theory is a theory of monopole we provide a new interpretation of Skyrme theory, that the theory can also be viewed as an effective theory of strong interaction which is dual to QCD, where the monopoles (not the quarks) are confined through the Meissner effect. This dual picture leads us to predict the existence of a topological glueball in QCD, a chromoelectric knot which is dual to the chromomagnetic Faddeev-Niemi knot in Skyrme theory, whose mass and decay width are estimated to be around 60 GeV and 8 GeV . As importantly, the existence of the magnetic vortex and the magnetic vortex ring in Skyrme theory strongly indicates that the theory could also be interpreted to describe a very interesting low energy condensed matter physics in a completely different environment. These new interpretations of Skyrme theory puts the theory in a totally new perspective.Keywords: Meissner effect in Skyrme theory, chromoelectric knot in QCD, Faddeev-Niemi knot in condensed matter physics.

A new Lorentz gauge gravity model with R 2 -type Lagrangian is proposed. In the absence of classical torsion the model admits a topological phase with an arbitrary metric. We analyze the equations of motion in constant curvature space-time background using the Lagrange formalism and demonstrate that the model possesses a minimal set of dynamic degrees of freedom for the torsion. Surprisingly, the number of torsion dynamic degrees of freedom equals the number of physical degrees of freedom for the metric tensor. An interesting feature of the model is that the spin two mode of torsion becomes dynamical essentially due to the non-linear structure of the theory. We perform covariant one-loop quantization of the model for a special case of constant curvature space-time background. We treat the contortion as a quantum field variable whereas the metric tensor is kept as a classical object. We discuss a possible mechanism of an emergent Einstein gravity as a part of the effective theory induced due to quantum dynamics of torsion.

It has been shown that 1,25-dihydroxyvitamin D3 has a photoprotective effect against UVB injury in mouse skin and cultured rat keratinocytes by induction of metallothionein (MT). Calcipotriol is a synthetic analogue of 1,25-dihydroxyvitamin D3 with equipotent cell regulating properties, but with a lower risk of calcium-related side effects. The aim of the present study was to see whether calcipotriol has a photoprotective property both in vitro and in vivo. We examined the effect of calcipotriol on UV-induced damage of cultured human keratinocytes through a cell viability assay, and measurement of DNA synthesis by cultured keratinocytes, on UV-induced damage of mouse skin and on minimal erythema dose (MED). We found that calcipotriol was protective against UVB-induced reduction in DNA synthetic activity of cultured keratinocytes in relatively low doses (20 and 40 mJ/cm2) of UVB. With phototesting following application of calcipotriol, five subjects among 10 healthy volunteers and three among six psoriasis patients showed an increase in MED compared with the vehicle-treated site. These findings imply that calcipotriol may be photoprotective and that more extensive studies with various doses of UV irradiation and modes of calcipotriol delivery are required.