Summary: The prevalence of cryptococcal meningitis has been investigated in 39 animals which comprised 36 dogs, 2 monkeys and 1 cat. Cryptococcus neoformans was isolated from the infected brains of 2 dogs on mycological media. The pathogen was also demonstrated in the brain tissues of the animals by potassium hydroxide technique. The histopathological examination revealed liquefaction of the brain surrounded by gliosis and a large number of yeast‐like cells with or without budding compatible with Cryptococcus neoformans. The disease could not be recorded from monkeys and the cat. The epidemiological investigation helped to establish the source of infection pigeon dropping in one ten year old male dog who was kept as watch animal in a poultry farm in Delhi. The isolates of Cryptococcus neoformans recovered from the clinical as well as environmental materiais were found to be pathogenic to swiss albino mice. It has been emphasized that cryptococcosis should be considered in the differential diagnosis of meningitis in small animals particularly canine. Zusammenfassung: 39 Tiere mit Meningitis 36 Hunde, 2 Affen, 1 Katze wurden auf Krypto‐kokkose untersucht. Cryptococcus neofomans konnte aus den men von 2 Hunden auf mykologischen Nährböden isoliert werden. Der Erreger ließ sich auch im kalilaugenpräparat nach‐weisen. Die Histologie zeigte Liquefaktion des Hirngewebes mit umgebender Gliosis und zablreiche SproßBzellen, die denen von Cryptococcus neoformans entsprachen. Bei den Men und der Katze wurde keine Kryptokokkose festgestellt. Bei einem 10 Jahre alten Hund ließ sich als Infek‐tionsquelle Taubenkot ermitleln. Die Pathogenität der Isolate mde im Tierversuch an Albinmäusen überpriift. Es wird darauf hingewiesen, daß die Kryptokokkose bei differentialdiagnostischen Überlegungen zur Meningitis kleiner Tiere, insbesondere bei Hunden, zu berücksichtigen ist.
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