The objective of this experiment was to measure the influence of virginiamycin on the apparent ileal digestibility (AID) of AA by growing pigs. Fifteen barrows were surgically equipped with a T-cannula in the distal ileum and used in the experiment (initial BW = 35.0 +/- 2.7 kg). Animals were randomly allotted to 3 dietary treatments with 5 pigs per treatment during a 6-wk experiment. Dietary treatments included 1) a basal corn-soybean meal diet, 2) the basal diet supplemented with 11 mg/kg of virginiamycin, and 3) the basal diet supplemented with 22 mg/kg of virginiamycin. Pigs were fed their respective treatment diets during wk 2, 3, and 4, but during wk 1, 5, and 6, all pigs were fed the basal diet. Ileal samples were collected on d 6 and 7 of each week. Results showed that the AID of all indispensable AA, except Arg, His, and Ile, increased (P < 0.05) during wk 2, 3, and 4 compared with wk 1 in pigs fed the diet containing 11 mg/kg of virginiamycin. Pigs fed 22 mg/kg of virginiamycin during wk 2, 3, and 4 had increased (P < 0.05) AID of Trp and Val during these weeks compared with the AID in wk 1. However, the increased AID of AA did not carry over to wk 5 and 6, when virginiamycin was withdrawn from the diet, regardless of the inclusion rate. In pooled data from wk 2, 3, and 4, the AID of CP, the mean of all indispensable AA, and Ile, Leu, Met, Phe, Trp, and Val increased (linear, P < 0.05) as virginiamycin was added to the diets, whereas a tendency (P < 0.10) for a linear or quadratic increase was observed for His, Lys, and Thr. These results indicate that addition of virginiamycin to corn-soybean meal diets fed to growing pigs increases the AID of AA, but this effect is not maintained after the removal of virginiamycin from the diet.
Problem statement: The objective of this experiment was to determine the effects of carbadox on Apparent Ileal Digestibility (AID) of Amino Acid (AA) by nursery pigs. Approach: Fifteen weanling barrows (initial BW: 9.6 kg) were surgically fitted with a T-cannula in the distal ileum. Animals were randomly allocated to three dietary treatments with five pigs per treatment during a 6- period experiment. Dietary treatments included: (1) a basal diet (BD) containing mainly corn and soybean meal, (2) BD + 27.5 mg kg-1 of carbadox and (3) BD + 55.0 mg kg-1 of carbadox. Treatment diets were provided during period 2-4; the BD was fed to all pigs during period 1, 5 and 6. Ileal samples were collected on d 6 and 7 of each period. Results: In pigs fed only the BD throughout the experiment, the AID of CP and many AA was greater during period 2-4 than during period 1 (p<0.05). This showed that the AID of CP and AA increased during the first few wk of the experiment. This analysis showed that pigs fed the diet containing 55.0 mg kg-1 of carbadox had greater increases (p<0.05) in the AID of CP and most AA from period 1 to period 2-4 than pigs that were fed the diet containing no carbadox. The AID for some AA was less during period 5 and 6 compared with period 2-4 for pigs fed diets supplemented with 27.5 or 55.0 mg kg-1 of carbadox (p<0.05). This observation suggests that there is no carryover effect of carbadox on AA digestibility. Conclusion: Inclusion of carbadox at 55.0 mg kg-1 in diets fed to weanling pigs increased the AID of AA, but carryover effects of dietary carbadox were not observed
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