The current study provides a comprehensive overview and analysis of the lignan literature. Data for the current study were extracted from the electronic Web of Science Core Collection database via the search string TOPIC = ("lignan*") and processed by the VOSviewer software. The search yielded 10,742 publications. The ratio of original articles to reviews was 14.6:1. Over 80% of the analyzed papers have been published since the year 2000 and nearly 50% since the year 2010. Many of the publications were focused on pharmacology, chemistry, and plant sciences. The United States and Asian countries, such as China, Japan, South Korea, and India, were the most productive producers of lignan publications. Among the 5 most productive institutions was the University of Helsinki in Finland, the country that ranked 9 th . Nineteen journals collectively published 3,607 lignan publications and were considered as core journals. Their impact factor did not correlate with the proportion of uncited papers. Highly cited publications usually mentioned phytoestrogen, isoflavone, daidzein, enterodiol, enterolactone, equol, genistein, and isoflavonoid. Cancer (e.g., breast cancer), cardiovascular disease, and antioxidation were the major themes. Clinical trials were estimated to contribute to 0.2-1.1% of the analyzed body of literature, so more of them should be conducted in the future to substantiate the beneficial effects and optimal dose of lignan intake in humans. Moreover, researchers can refer to these findings for future research directions and collaborations.

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In this study, we investigated the effect of modification of 12 d storage conditions of quail eggs from two flocks: at 17–20 weeks of life (A) and 36–39 weeks of life (B) on the incubation time, hatch window (HW), hatching results and chicks quality. The eggs were divided into experimental groups: COI = no pre-incubation (PI); SPIDES = were treated with 4 h PI, delivered at 4, 6, 8 and 10 d of storage; EG SPIDES = were treated with variable time of PI according to the scheme 5 d – 2 h, 7 d – 3 h, 9 d – 5 h and 11 d – 6 h. In addition, in each group, half of the eggs were turned (T) every 12 h, which is indicated as COI T, SPIDES T and EG SPIDES T. Pre-incubation was conducted at 37.8°C and 50–55% RH. It has been demonstrated that both storage profiles contribute to shortened incubation time, yet the HW is deteriorated if T is not applied. The benefits resulting from the EG SPIDES profile is an increase of 2.3 points in the “average score of all chicks” index compared to the COI group. In summary, the use of PI and T, and in particular the EG SPIDES profile with the concomitant use of T during long storage of quail eggs is recommended to obtain a considerable improvement of hatching results and chick quality.