Nanoparticles have received much recent attention in areas such as chemistry, physics, materials science, life sciences and engineering. Many physical and chemical methods have disadvantages such as high costs, the use of chemicals that are harmful to the environment and health. The green nanoparticle synthesis approach, using plant extracts as a capping agent of nanoparticles, is the right solution to produce nanoparticles that are effective and environmentally friendly. Micro and macroalgae in the use of nanoparticle synthesis are increasingly being developed. However, the use of Sargassum in chemical applications has not been fully explained, and there are still some drawbacks that must be overcome. Sargassum spp. biomass has been recognized as a natural, renewable, and cost-effective material to become a capping agent for nanoparticles. This review is a summary highlighting the potential of metal-Sargassum composite based materials as an alternative to biological protective activities, such as antibacterials. Synthesis and characterization of materials, key factors influencing material performance, and distribution of Sargassum in Indonesia are considered by the Government of Indonesia and investors in seeing opportunities to use Sargassum as an advanced material.
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