percentage and kinetic growth rate (KGR) as percentage/ week were used to assess the increase of the liver volume.Results: In this study,142 patients were enrolled. Sequential pre-and post-CT-scans were available for 53 patients (32 for CRLM, 21 for pCCA). Liver segment II and III volumes increased significantly after PVE in both groups (P < 0.001). pCCA patients with cholangitis (n=4) had an almost blunted DH (P = 0.042). DH and KGR did not differ (P = 0.719 and P = 0.968, respectively) between drained and undrained pCCA patients. Higher initial bilirubin level before biliary drainage was correlated with less PVEinduced DH (r=-0.727, P = 0.007). The bilirubin level and bile duct diameter before PVE was not associated with DH and KGR. Conclusion: Initial bilirubin levels before biliary drainage were negatively correlated with PVE-induced liver hypertrophy in patients with pCCA. Biliary duct diameter and bilirubin level right before PVE seems less of influence on PVE induced hypertrophy.
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