A phytochemical investigation of the methanolic extract of the inner root bark of Kokoona zeylanica Thwaites (Celastraceae) has resulted in the isolation and identification of dulcitol and (-)-I'-O-methylepigallocatechin. The chemotaxonomic significance and biological activity of dulcitol are discussed.Kokoona zeylanica Thwaites (Celastraceae), a plant having restricted distribution in Sri Lanka and South India, has an outer bark with a brilliant yellow color (1). According to Thwaites (2), the powdered yellow bark is used as a cephalic snuff to relieve headaches. A paste prepared by mixing powdered bark with water is dried and formed into flat pieces for use by the villagers in Sri Lanka in place of toilet soap (3). The genus Kokoona has eight species (2,4), all distributed in the Asian subcontinent.Our previous work on the stem bark of K. zeylanica resulted in the isolation and characterization of friedelin, D:A-friedo-oleanan-3,21-dione, 21a-hydroxy-D: A-friedo-olean-3-one, eight new D :A-friedo-oleanane triterpenes (5-7) and zeylasterone, the first natural phenolic 24-nor-D :A-friedo-oleanane (8). In continuing our studies, we have investigated the methanolic extract of the inner root bark of K. zeylanica. In this paper we present the isolation and identification of dulcitol and (-)-4'-0-methylepigallocatechin (1). A preliminary report of this work has already appeared (9). Our studies on the minor constituents of this extract will be reported in a subsequent paper.
Three new 9‐(N‐alkynyl)acridinamines 5, 6 and 7 have been synthesized from 9‐chloroacridine using a simple aromatic nucleophilic substitution reaction.
Azapropazon (1) ist in Lösung und im kristallinen Zustand photoinstabil2)6). Wie von uns mitgeteilt6, enthält das Photolysat einer methanolischen Lösung von 1 als Hauptprodukt 3‐Dimethylamino‐7‐methyl‐1, 2,4‐benzotriazin (2), das zu 3‐Methylamino‐7‐methyl‐1,2,4‐benzotriazin (3) weiter abgebaut wird.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.