The Simons Foundation Autism Research Initiative (SFARI) has launched SPARKForAutism.org, a dynamic platform that is engaging thousands of individuals with autism spectrum disorder (ASD) and connecting them to researchers. By making all data accessible, SPARK seeks to increase our understanding of ASD and accelerate new supports and treatments for ASD.

No abstract

Trityl bromide was obtained from Aldrich and 6-iodo-l-heptene(1) was prepared from its tosylate and sodium iodide as reported earlier.6 5-Chloro-l-cyclooctene (4), 5-bromo-l-cyclooctene (3), and 5-iodo-l-cyclooctene (2) can be obtained in nearly quantitative yield by Pritzkow's method of adding dry HX to 1,5-cyclooctadiene in CH2C12.13Gas chromatographic analyses were conducted on a Hewlett-Packard Model 700 instrument using a FID detector and packed columns. Quantitative GLC analyses were obtained with the use of response factor corrected peak areas using internal standards.Infrared spectra were recorded on a Perkin-Elmer Model 621 spectrophotometer.Mass spectra were obtained on a Varían MAT 112S, and for EPR studies spectra were recorded on a Varían E 109 ES.General Procedure for Reduction of Alkyl Halides. The appropriate amounts of alkyl halide (0.1 M) and metal hydride (0.2 M) were combined in a reaction tube under N2 in THF and shielded from light. For the EPR study, the reagents were combined in an EPR tube under N2. In those cases where DCPH or DCPD were employed, the additive was added to the metal hydride, followed by the addition of the appropriate alkyl halide. Control experiments showed that no reaction occurred between LiEtgBD and DCPH, as determined by the constancy of the P-H (13) Franz, H.

No abstract