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(1972). Archives of Disease in Childhood, 47, 373. Growth of radiologicaily determined heart diameter, lung width, and lung length from 5-19 years, with standards for clinical use. Heart diameter, lung width, and lung length have been measured on serial chest radiographs taken at annual intervals on 84 boys and 78 girls who were tuberculosis contacts but free of disease. Most were followed from age 5 or 6 to age 15; some till age 20. Supplementary data were available on 46 boys and 40 girls from the Harpenden Growth Study.Centile standards for these measurements and for lung area (width x length) at ages from 6 to 19 years are presented for clinical use. Mean velocity curves are given over the same age range.The lungs are exceptional in that the adolescent growth spurt is of similar magnitude in both boys and girls, and the girls' mean value does not exceed the boys' mean value in lung width even at the peak of the girls' spurt, as it does in all other body measurements except those of head and feet.The age at peak velocity for lung width and heart diameter coincides with the age for peak height velocity; the peak for lung length occurs about 6 months later than that for lung width.The heart diameter has an adolescent spurt of about equal magnitude in both sexes in these data. At age 6, heart diameter is 78% and 81 % of its adult value, respectively, in boys and girls, compared with figures of 66 to 67% for lung width, 62 to 63% for lung length, and 66 to 67% for height. A wide variation in the level of the diaphragm was found, but by the age of 20 the diaphragm was below the anterior end of the 5th rib in both males and females. In women no case fell below the 6th rib, but in men some 18% fell below it.

The precise nature of the leukocytic reactions during measles still remains a subject concerning which there are surprising differences of opinion. Although it is generally held that a leukocytosis is present during the incubation period, followed as a rule by a leukopenia during the acute febrile stage,1 there is a lack of agreement regarding the changes in the differential count. It was early pointed out by several investigators 2 that the fall in the blood count was due chiefly to a diminution in the number of lymphocytes. Diametrically opposed to this finding, however, have been the reports of a lymphocytosis occurring simultaneously with the rash.3 Moreover, it has been maintained 4 that variations in the number of polymorphonuclear cells principally account for the leukocytosis or the leukopenia observed in the different phases From the Hospital of the Rockefeller Institute for Medical Research.