Surgical treatment for traumatic aneurysms is challenging because most of TICAs are histopathologically pseudoaneurysms. It may be technically difficult to perform direct surgery of aneurysms especially located in the posterior circulation, but when the treatment is successful, the outcome was favorable.
Acute large vessel occlusion is treated with endovascular thrombectomy. We encountered a patient in whom the internal carotid artery (ICA) was injured by direct aspiration through a balloon guide catheter (BGC). Case Presentation: The patient was an 82-year-old woman being treated with oral warfarin for atrial fibrillation. Endovascular thrombectomy was performed for right ICA occlusion presented with left hemiplegia when direct aspiration was applied through BGC which placed into the right ICA, extravasation was noted on imaging immediately after its application. Hemostasis was acquired by coil embolization, but extensive subarachnoid hemorrhage was noted on postoperative CT and the patient died after 3 days. Conclusion: The direct aspiration technique through BGC should be carefully performed because it may have a risk of vascular injury.
This study evaluated whether cell sheets containing a network of lymphatic endothelial cells (LECs) promoted lymphangiogenesis after transplantation in vivo. Cell sheets with a LEC network were constructed by co-culturing LECs and adipose-derived stem cells (ASCs) on temperature-responsive culture dishes. A cell ratio of 3:2 (vs. 1:4) generated networks with more branches and longer branch lengths. LEC-derived lymphatic vessels were observed 2 weeks after transplantation of a three-layered cell sheet construct onto rat gluteal muscle. Lymphatic vessel number, diameter and depth were greatest for a construct comprising two ASC sheets stacked on a LEC/ASC (3:2 ratio) sheet. Transplantation of this construct in a rat model of femoral lymphangiectomy led to the formation of functional lymphatic vessels containing both transplanted and host LECs. Further development of this technique may lead to a new method of promoting lymphangiogenesis.
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