Hydroxyapatite is the main component of natural hard tissues, such as teeth and bone. It has been studied extensively as a candidate biomaterial for its use in prosthetic applications. Hydroxyapatite was formulated as Ca10(PO4)6(OH)2 and it has a high stability under physiological conditions. Also hydroxyapatite can be synthesized using dierent calcium and phosphorus precursors. In this study, biomimetic hydroxyapatite powder has been synthesized simulating physiological conditions. Synthetic body uids which have the same composition as human blood plasma instead of pure water were used as precipitation media to obtain biological conditions. Recent research involved the eect of dierent Ca-precursors however aim of this study is to determine the eect of phosphorus resources. In this study, the synthesis of hydroxyapatite powder is carried out by using biomimetic method in synthetic body uids. OPA] were used as Ca-and P-precursors. Chemical structures of synthesized powders have been examined by Fourier transform infrared and X-ray diraction. Results showed that synthesized powders have a pure hydroxyapatite structure. However, ADHP precursors have an unfavorable eect on sintered hydroxyapatite powders. Using ADHP phase transition was caused in pure hydroxyapatite structure and apatite and whitlockite were observed as secondary phases. Their particle size, surface area determination and morphological structures have been characterized by Zeta-Sizer, biomimetic hydroxyapatite the BrunauerEmmettTeller analysis and scanning electron microscopy images, respectively. As a result dierent starting materials have aected the structure, particle size and morphological properties of biomimetic hydroxyapatite.
Hydroxyapatite is the main component of human hard tissues such as bones and teeth. Because it has a great biocompatibility with human organism, it is used as biomaterial with the purpose of form and repair hard tissues. Hydroxyapatite is formulated as Ca 10 (PO 4 ) 6 (OH) 2 and shows high stability under physiological conditions. In this study, biomimetic hydroxyapatite powder has been synthesized using by synthetic body fluids which has the same composition as human blood plasma. Moreover, the effect of different precursors on properties of synthesized powders has been investigated. ] were used as precursors. Mainly literature focused on the synthesis of hydroxyapatite powders was carried out using chemical method. However, in this study, the synthesis of hydroxyapatite powder is carried out using biomimetic method. Chemical structures of synthesized powders have been investigated by the Fourier transform infrared and X-ray diffraction methods. Results showed that synthesized powders have a pure hydroxyapatite structure. Surface area of the synthesized powders was measured by the Brunauer-Emmett-Teller method. Morphological structures have been characterized by using scanning electron microscopy. Furthermore, particle size of powders was calculated using the Brunauer-Emmett-Teller method. It was clearly seen that morphological properties of biomimetic hydroxyapatite have affected the use of different calcium precursors.
The aim of this study was the compare the properties of hydroxyapatite as a function of two dierent methods (chemical and biomimetic precipitation). Powder products were called as chemical hydroxyapatite for chemical method and biomimetic hydroxyapatite for biomimetic method. Precipitated powders with both methods were characterized by Fourier transform infrared, X-ray diraction, X-ray uorescence and measurements of hardness and density. Chemical analysis results showed that dried-biomimetic hydroxyapatite sample consists of hydroxyapatite [Ca10PO4)6(OH)2] as main phase and beta-tricalcium phosphate (β-TCP) as secondary phase and dried-chemical hydroxyapatite sample also includes pure hydroxyapatite phase. Chemical hydroxyapatite and biomimetic hydroxyapatite powders were sintered using by spark plasma sintering method. Vickers hardness values of sintered disk samples were measured. Furthermore chemical structure of the nal products was analyzed. Also density values of chemical hydroxyapatite and biomimetic hydroxyapatite disks were measured. Finally it is concluded that dierent precipitation methods aect hydroxyapatite properties and this can be an advantage for biomedical applications.
Hydroxyapatite [HA; Ca 10 (PO 4) 6 (OH) 2 ] which composes inorganic phase of bones and teeth is one of the biomedical materials for artificial bone, reconstruction of broken or disordered bones, coating of metallic biomedical materials and dental surgery with its great biocompatibility. In this study, HA powders were synthesized from aqueous suspensions containing H 3 PO 4 and Ca(OH) 2 with 1.67 Ca/P ratios (chemical HA, CHA) and second process is carried out in simulated body fluids consisting of (NH 4) 2 HPO 4 and Ca(NO 3) 2 •4H 2 O as biomimetic hydroxyapatite (BHA). Moreover, properties of bovine HA (BoHA) and commercial HA (CoHA) were compared with properties of synthesized HA powders. Chemical structures of synthesized powders have been examined by the Fourier transform infrared technique and X-ray diffraction. The results showed that BHA powders have a pure HA content and no secondary phase, CHA also has monetite phase as secondary phase with HA in its structure. Particle size analysis was carried out with laser particle sizer and zeta-sizer, surface area of powders has been analyzed by the Brunauer-Emmett-Teller technique. Powder morphology is determined using scanning electron microscopy. As a result two different synthesis methods affected properties of HA powders.
Hydroxyapatite (HA) is the major component of the natural hard tissues such as teeth and bone. It has been studied extensively as a candidate biomaterial for its use in prosthetic applications. However, the main weakness of this material lies in its poor mechanical strength which makes it unsuitable for load-bearing applications. On the other hand zirconia (ZrO2) powder has been widely studied because of its high strength and fracture toughness and good biocompatibility. Therefore, the addition of zirconia phase into HA will improve the mechanical properties and biocompatibility of HA ceramics. The present study focused on coating of HA-ZrO2 on commercially pure titanium (cp-Ti) using novel biomimetic sol-gel method. The HA-ZrO2 coatings produced with BSG method were exhibited highly crystalline and pure structure. The coating thickness of the samples was not significantly influenced by the change in gelatin concentration and volume. It was concluded that the suggested coating method is a useful method to produce a biomimetic coating layer on the cp-Ti sample surfaces.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.