The most common perceived benefits of RT-CGMS are prevention of hypoglycemia and decrease in hypoglycemia-related anxiety. Negative effects are uncommon and seem to be unlikely to affect the decision to use RT-CGMS for a LT. A ST trial seems to be a valuable tool for the patient/caregiver in determining whether to purchase the device and in setting realistic expectations of its potential benefits.
The risk of hypothalamic-pituitary dysfunction in SOD is highest ≤ 2 years of age and when both optic nerve hypoplasia and dysgenesis of septum pellucidum/corpus callosum are present, suggesting a need for more frequent follow-up and screening tests for hypothalamic-pituitary dysfunction in these patients.
The aim of this study is to determine the underlying etiology of failure to thrive (FTT) in infants and toddlers referred to an outpatient pediatric endocrinology clinic. A chart review was done on FTT referrals to a pediatric endocrinology outpatient clinic between 2002 and 2005. Majority of patients (51.5%) had a purely nutritional deficiency. The endocrine etiologies included short stature due to being small for gestational age, constitutional or familial short stature (28.9%). The third most common etiology was gastrointestinal disease. Endocrine causes of FTT seem to be rare even in the selected population of patients referred to pediatric endocrine outpatient clinics. In the primary care setting, nutritional assessment and consultation seem to be adequate in the majority of cases. Only a small percentage of the patients with FTT will require a multidisciplinary approach and more extensive work-up.
We present the first childhood case of lymphocytic hypophysitis which is an autoimmune inflammatory disorder of the pituitary gland. Although this is a rare condition in adults, it also needs to be considered in the pediatric population. Conservative management is preferred unless there are signs of increased intracranial pressure. Most importantly, close monitoring for multiple hormone deficiencies is indicated in this condition.
Primary hyperparathyroidism in middle-aged women is most commonly diagnosed after detecting incidental hypercalcemia during a routine blood test 1 ' 2 . Occasionally, diagnosis of hyperparathyroidism in a young asymptomatic mother is made when the infant presents with hypocalcemia 3 ' 7 . Here we present an infant with severe prolonged hypocalcemia secondary to maternal asymptomatic hyperparathyroidism.A 7 week-old boy was referred to Dokuz Eylül University Children's Hospital because of recurrent hypocalcemic convulsions. He was a full term baby born to a 24 year-old mother by normal spontaneous vaginal delivery with a birth weight of 2300 g. He has had no problems during the immediate postpartum period and the first 3 weeks of life. He had been exclusively breast-fed and had adequate weight gain. At 3 weeks of age, he started having several tonic-clonic convulsions and was admitted to a local government hospital. On laboratory tests, he was found to have profound hypocalcemia and was given intravenous calcium infusions for 5 days and discharged home. At age 40 days, his tonic-clonic convulsions recurred. Laboratory tests revealed calcium of 4.7 mg/dl and phosphorus of 5.4 mg/dl. His family history was unremarkable except that his mother had passed several stones during her pregnancy. On physical examination, he was 3.7 kg (10 th percentile) in weight and 50 cm (3 rd percentile) in length; head circumference was 37 cm (2 SD). He had no
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