Background: Exposure of potato tubers to light causes accumulation of glycioalkaloids in the tubers and overdose of glycoalkaoids are associated with some toxicity. This study aims to investigate the effect of consuming sunlight exposed tubers of Irish potato on some selected tissues of rats. Methods:Freshly harvested tubers of Solnum tuberosum were purchased from a farmland and were randomly grouped into five groups. Groups 1- 4 consisted of tubers exposed to sunlight (including visible and invisible light e.g. ultraviolet) for a period of 1, 2, 3, and 4 week(s), respectively, while group 5 served as the control and consisted of freshly harvested tubers of Irish potato that have not been exposed to sunlight. The glycoalkaloids content was determined in both the non-exposed (control) and sunlight exposed tubers. Thereafter the tubers were formulated as diet and administered to rats. Biochemical analyses on serum lipid profile, enzymes of selected tissues (serum, liver, and kidney) and lipid peroxidation were carried out. Results: The results showed that the total glycoalkaloids content of the exposed sunlight groups (230, 250, 270, and 300 mg/kg fresh weight, respectively) significantly increased compared to the control group (100 mg/kg fresh weight). A significant reduction (P < 0.05) in activities of alanine aminotransferase, aspartate aminotransferase and a significant upsurge (P < 0.05) in alkaline phosphatase activity was observed in the selected tissues of sunlight-exposed potato tuber animal groups compared to the (non-exposed) group. Lipid peroxidation assessment revealed a significant upsurge (P < 0.05) in malondialdehyde formation and a mild alteration in serum lipid profile. Conclusion: The study concluded that consumption of sunlight exposed Solanum tuberosum tubers may pose a threat on vital organs of the body irrespective of duration of exposure.

Coronavirus disease (COVID-19) has had devastating impacts on the global economy and public health. This study aimed to assess the level of COVID-19 vaccine acceptance, hesitancy, and associated factors among staff and students of the Federal University of Health Sciences Otukpo, Benue State, Nigeria. A web-based cross-sectional survey was conducted between November 2021 and April 2022, and data were collected and analyzed using descriptive and inferential statistics. Of the 150 completed and analyzed questionnaires, the majority of respondents (80.0%) were between 16 and 45 years old. The study found that 58.4% of participants indicated vaccine hesitancy, with skepticism about the vaccine's fast production/rollout and fear of vaccine side effects being the most common reasons for hesitation. Respondents' age, religion, and category were significant factors influencing vaccine acceptance and hesitancy (P &lt; 0.05). The university community has a high level of awareness of COVID-19 but low vaccine acceptance, resulting in high levels of vaccine hesitancy. The study recommends that policymakers and public health officials should prioritize testing and vaccination for job categories with higher risk of exposure to COVID-19. They should provide accurate information about COVID-19 testing and vaccination and implement workplace-based testing and vaccination programs. These interventions can help to increase COVID-19 testing and vaccination uptake among the university community and mitigate the spread of COVID-19.