Aim This study aims to determine the effect of COVID‐19 anxiety levels of healthcare professionals on their working life quality. Method The sample of the descriptive, cross‐sectional and correlational study consisted of healthcare professionals working in two university hospitals in western Turkey between May and July 2021. We used the “Personal Information Form, Coronavirus Anxiety Scale, and Working Life Quality Scale” as data collection tools. We used numbers and percentage calculations, arithmetic mean, median (25th–75th percentile), Mann–Whitney U test, Spearmen correlation analysis and Linear Regression analysis to analyse the data. Results The mean score on the Quality of Life Scale of healthcare professionals was 3.74 ± 0.28, and the mean score on the Coronavirus Anxiety Scale (CAS) was 9.66 ± 6.06 (min. 0; max. 20). We found a negative and weakly significant relationship between the mean score of the CAS of healthcare professionals and the mean score of the employee quality of life scale. According to the results of the multiple linear regression analysis, we found the factors significantly affecting the anxiety states of healthcare professionals related to the Coronavirus are the quality of working life, age, sex and the state of caring for a patient with COVID‐19. Conclusion As a conclusion of this study, it was determined that healthcare professionals experienced anxiety, and anxiety decreased as ages, working years and the number of children they have increased. In addition, it was determined that as the anxiety of healthcare professionals increased, the quality of working life decreased.

Healthcare institutions are organizations with a complex structure where there is a high work stress and it is of utmost importance that services are provided without errors in this complexity. Nowadays, when the hospital management becomes increasingly complex, hospital managers are in a position that influences the success of the hospitals the most. While this situation necessitates the managers to use their time in a more rational and efficient manner, giving a senseless workload to the managers would surely negatively affect the individual and organizational productivity (Karsavuran, 2014). In other words, exposure of the healthcare professionals to mobbing in the professional life causes depressive symptoms to arise, this situation leading to the individual negatively evaluating the quality of his life. As a result, decrease in the job satisfaction of the individual, low performance and reluctance towards the job occur (Yavuzer and Civilidag, 2014).   Therefore, it is proposed to clarify the arrangements that prevent managers from applying psychological abuse to their subordinates when determining the superior-subordinate relationships (Yıldız et al., 2013). In this study the titles will include definition of mobbing in health sector, results of mobbing.

Significant decrease in the rate of population growth across the world and the rise in the average life expectancy in recent years has caused and increase in the rate of elderly in general population and has drawn attention to demographic ageing process in the world. Employment of the workforce at an advanced age will provide some development in the economic apportinuties of them and will increase their participation in social and cultural fields. Therefore discussing elderly indivudial's problems in working life is important especially to produce sensible and lasting solutions for active ageing and to be able to deal with many negative consequences caused by demographic transition in the final stage. The study intented to the descriptive aim as prospective was carried out to determine the problems of older workers in Kirklareli. In the study random sampling method is used to code data statistical analysis is made by using SPSS 13 Programme. According to the concequences of the study, it was determined that 67% of employers don't know using tecnology, 47% of them prefer young employees for the hard work and prefer older employees for the light work. Also it was determined that 67% of the employees experience physical problems, 87% of the employees complain with negative impacts of stress to their working quality, 73% of them think that they are exposed to the aged discrimination and 34% of them experience chronic fatigue. ÖzetSon dönemlerde dünyada görülen nüfus artış hızındaki önemli azalış ve ortalama yaşam beklentisindeki yükseliş, genel nüfus içindeki yaşlı nüfus oranının artmasına neden olmakta ve dünyadaki demografik yaşlanma sürecine dikkati çekmektedir. İleri yaş işgücünün istihdamı, söz konusu kesimin ekonomik imkânlarını geliştirmenin yanında, onların sosyal ve kültürel alanlara da katılımlarını arttıracaktır. Tanımlayıcı amaca yönelik prospektif olarak gerçekleşen çalışma; Kırklareli İli yaşlı işgücünün sorunlarını belirlemek amacıyla gerçekleştirildi.Olasılıksız örnekleme yöntemlerinden gelişigüzel örnekleme yöntemiyle toplanan veriler kodlanarak, very analizi SPSS 13 paket programında gerçekleştirildi. Çalışma sonucunda, işverene özgü; teknoloji kullanımının bilinmediği (% 67) ve işverenlerin % 47'sinin ağır iş yükü olan işlerde genç yaş grubunu; hafif derece işlerde ise ileri yaş grubunu istihdam etmek istedikleri belirlendi. İşçi açısından bakıldığında ise; % 67'sinin fiziksel rahatsızlık yaşadığı; iş yerinde yaşanan psikolojik gerilimin-stresin işçilerin % 87'sine negative yönde etkilediği, çalışma kalitesini ve iş doyumunu düşürdüğü; katılımcıların % 73'ünün yaşa bağlı ayrımcılığa maruz kaldığını düşündüğü ve %34'ünün kronik yorgunluk yaşadığı görüldü.

Background The CAAX-prenyltransferases farnesyltransferase (FTase) and geranylgeranyltransferase I (GGTase I) are heterodimers with a common α- (FTα) and unique β-subunits. Recently, α-subunits of species (e.g., human) that harbour an N-terminal proline-rich region (PRR) showed different dimerization behaviours than α-subunits without PRR (e.g., yeast). However, the specific function of the PRR has not been elucidated so far. Methods To determine whether the PRR is a conserved motif throughout eukaryotes, we performed phylogenetics. Elucidating the impact of the PRR on enzyme properties, we cloned human as well as rat PRR deficient FTα, expressed them heterologously and compared protein–protein interaction by pull-down as well as crosslinking experiments. Substrate binding, enzyme activity and sensitivity towards common FTase inhibitors of full length and PRR-deletion α-subunits and their physiological partners was determined by continuous fluorescence assays. Results The PRR is highly conserved in mammals, with an exception for marsupials harbouring a poly-alanine region instead. The PRR shows similarities to canonical SH3-binding domains and to profilin-binding domains. Independent of the PRR, the α-subunits were able to dimerize with the different physiological β-subunits in in vitro as well as in yeast two-hybrid experiments. FTase and GGTase I with truncated FTα were active. The KM values for both substrates are in the single-digit µM range and show no significant differences between enzymes with full length and PRR deficient α-subunits within the species. Conclusions Our data demonstrate that an N-terminal PRR of FTα is highly conserved in mammals. We could show that the activity and inhibitability is not influenced by the truncation of the N-terminal region. Nevertheless, this region shows common binding motifs for other proteins involved in cell-signalling, trafficking and phosphorylation, suggesting that this PRR might have other or additional functions in mammals. Our results provide new starting points due to the relevant but only partly understood role of FTα in eukaryotic FTase and GGTase I.

To determine the relationship between attitudes toward aging and old age, and successful aging in individuals with chronic disease aged 65 or over.Material and methods: The Attitude Scale toward Aging and Elderliness and the Successful Aging Scale were employed in this descriptive, cross-sectional, comparative study. Data were expressed as frequency, percentage, mean, and standard deviation and were analyzed using the Kolmogorov-Smirnov test, the t test, One-Way ANOVA, and Pearson correlation analysis. p values <0.05 were regarded as significant.Results: Individuals with chronic disease had greater difficulty in accepting old age, greater social exhaustion, greater abilities to cope with problems, and higher successful aging scores. Conclusion:This study shows that despite their negative attitudes toward old age, individuals with chronic disease had greater abilities to cope with problems and aged more successfully.

Aging, a common problem in almost all countries, both developed and developing, is expressed in terms of a decrease in global birth and death rates or, from a different perspective, an increase in mean life expectancy. Demographic aging, which may be regarded as both a threat and an opportunity, affects a very broad sphere, including basic health, the economy, social security, the saving-consumption balance, living arrangements, urbanization, and the family structure, and therefore brings different disciplines together. Looked at in greater detail, it is a subject that requires reflection and planning since it affects such areas as change in a country’s population structure, economic growth, labor markets, labor supply and productivity, development policies, public borrowing, health and social security policies, education policies, and urbanization policies. The fact that demographic aging is a common problem of both developed and developing countries raises the question of active and healthy aging policies. These policies are thought to play an important role in measures created or potentially created by aging. Discovery of the importance of individual capital accumulation and wide social capital has prepared the dissemination of active-healthy aging policies out of the idea that investment in individuals’ health, education, and participation opportunities will benefit both the individual and the community. The emergence of the ‘Age-Friendly Cities’ movement initiated by the World Health Organization is one concrete outcome of these policies. The first section of this study will discuss the concept of demographic aging and its relationship with active-healthy aging. The economic and social effects of demographic aging will then be discussed. Another section of the study will discuss the concept of age-friendly cities, their relationship with active aging, and their role against the impacts of demographic aging.

The purpose of this study is to conduct an overview of the psychologic and economic effects of the Covid-19 pandemic. It was performed as a review of studies published between March 2019 and August 2021 and as a systematic examination of the data yielded by these. Twenty-nine Turkish and international studies on the subject were accessed, and eight publications meeting the inclusion criteria were included in the study. All publications were examined via systematization in terms of methods and results. This systematic examination revealed that the psychologic situations and economies of many countries have been adversely affected by the Covid-19 pandemic, that the most important reason for this is restrictions experienced as a result of lockdowns, that the worst affected areas are the tourism, industry, and finance sectors, and that countries have endeavored to adopt their own precautionary measures. The adverse psychological and economic impacts of Covid-19 in almost all countries continue to represent a major problem. Significant scientific findings regarding the problem were yielded by systematizing studies on the subject. We think that these findings are important in terms of determining the scope of future studies and the requisite measures for resolving the problem.

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