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Porous organic cages have shape persistent cavities which provide a suitable platform for encapsulation of guest molecules with size suitably fitting to the cavity.

Hispanics are a growing population in the United States with an expected 14 million women of child-bearing age by 2020, and the prevalence of preconception folic acid supplement use is low in this group with a high risk of neural tube defects. Promotion of voluntarily fortified corn masa flour can lower neural tube defects in Hispanics. Mandatory corn masa fortification will be a more effective public health policy.Birth Defects Research 109:38-48, 2017. © 2016 Wiley Periodicals, Inc.

Neutropenia has been reported in pediatric heart transplant recipients, but its association with infectious morbidity and mortality is unknown. We sought to determine neutropenia's prevalence and impact on infection, rejection, and survival. A retrospective analysis of pediatric heart transplant recipients from March 2005 to August 2015 was performed. Demographics, medications, infection, and rejection data were collected. Of 142 pediatric heart transplant recipients, 77 (54.2%) developed neutropenia within 4.7 months [3.3-12.1 months] of transplant. In all patients, the adjusted 5-year cumulative incidence of neutropenia was 30.2%. Fifty-one patients (66.2%) had recurrent neutropenia. Six of 14 tested had positive antineutrophil antibodies. Medications associated with neutropenia were decreased in 15 (19.5%) and discontinued in 42 (54.4%) patients with no change in 1-year rejection rates compared to published data. Fifteen patients developed infection within 30 days of neutropenia and two from 30 days to 1 year, with an infection rate similar to the non-neutropenic group. There was no significant difference in survival, ANC, rate of rejection or PTLD in neutropenic patients with and without infection at median follow-up (5.5 years). Neutropenia is common in pediatric heart transplant recipients. Neutropenia had <20% risk of associated infection, similar to non-neutropenic patients. Infection in neutropenic patients did not increase mortality.

Curcuma Longa is the scientific name of turmeric, a member of the Zingiberaceae family of plants. It has been used in Ayurvedic medicine in different countries since long ago. But now, it is more popularly known for its wound-healing and inflammation-relieving properties. Curcumin is the biologically active ingredient responsible for these actions of Curcuma Longa. It acts at different stages of wound healing and makes it heal more quickly. It prevents inflammation and helps the immune system of the body. It also exhibits more pharmacological properties like anti-cancerous, anti-microbial, anti-diabetic, etc. This review will explain how curcumin heals wounds and acts as an antioxidant and anti-inflammatory. Moreover, this will also shed light on the latest formulations of curcumin, treating wounds and inflammation. Topical formulations are often used for immediate response and effect because they are very strong and provide relief quickly.

The study's objectives was to determine the frequency of various clinical manifestations of congenital adrenal hyperplasia in children. Materials & Methods: The research methodology is descriptive and cross sectional. The event was held at the Department of Pediatric Medicine at DHQ Hospital in Faisalabad. The study will last from September 29th to March 28th, 2019. A total of 90 children with congenital adrenal hyperplasia of age 0-10 years of either gender were included. After taking informed written consent from all children’s parents, different clinical presentations (ambiguous genitalia, simple virilising and salt wasting) were noted in each patient. Results: Mean age of children was 4.84 ± 1.78 years. Out of the 90 patients, 62 (68.89%) were male and 28 (31.11%) were females with male to female ratio of 2.2:1. Mean duration of symptoms was 5.79 ± 2.59 days. In this study, I have found the ambiguous genitalia in 27 (30.0%), simple virilising in 17 (18.88%) and salt wasting in 59 (65.56%) children with congenital adrenal hyperplasia. Conclusion: This study has shown that the salt wasting is the most common clinical presentations of congenital adrenal hyperplasia in children followed by ambiguous genitalia and simple virilising. Keywords: Congenital adrenal hyperplasia, ambiguous genitalia, salt wasting.

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