Introduction Myofascial pain syndrome is a local disorder characterised by pathological myofascial constrictions and trigger points. One of the most popular sources of internet-based information for patients is YouTube, which provides a lot of videos related to myofascial pain syndrome, making it one of the top clinical conditions searched for on the site. This study aimed to examine the quality of the YouTube video content on myofascial pain syndrome. Method This study was designed as a cross-sectional study and used the YouTube video sharing website as the main source of data. A search of the relevant videos was performed by entering the words “myofascial pain syndrome” in June 2021. Video characteristics were recorded, and the quality of the videos was assessed according to the Journal of the American Medical Association (JAMA) benchmark criteria, the DISCERN Scale and the Global Quality Scale. Results A total of 322 videos were evaluated, 186 of which were subjected to analysis after applying the inclusion/exclusion criteria. The videos were categorised into groups, with 10 (5.4%) falling into the high-quality group, 16 (8.6%) into the intermediate quality group, and 160 (86%) into the low-quality group. The findings from the study showed that the most popular videos, the highest number of video likes and the highest number of video views were in the intermediate group, while the high-quality group had the lowest popularity level, number of video likes and number of video views (p ˂ 0.05). Conclusions Although there are videos with high-quality content on YouTube offering guidance to patients about the disease, it is important to keep in mind that inaccurate and deficient information about the disease may also be present on this platform.

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