Acanthosis nigricans (AN) is a skin disorder with a wide prevalence, depending on the concomitant disorder and other elements such as age, race, and Fitzpatrick skin type. This prevalence is 25% in general researches while more than 60% in overweight-specific researches. 1 The AN diagnosis depends on the presence of symmetrical dark brown hyperpigmentation, thickening in the affected area varies between 1 mm and 1 cm, and a velvety texture can occur especially in the flexural skin fold area. 2 The AN dermatological issue indicates the presence of systemic problems: metabolic disorder (mostly), endocrine syndrome, malignancy, medication side effects, and genetic factor, it resembles the apex of an iceberg, that leads the physicians to search for what of these disorders lies beneath. 3 The treatment aims to treat the underlying causes; however, the cosmetic resolution of the cutaneous lesion has an impact on the quality of