Atypical and unusual locations of psoriasis are very frequent. However, localized
linear psoriasis is rare, with few cases described in the literature. It is
characterized by a linear distribution of psoriasis lesions along Blaschko lines. We
report the case of a three years old child, who presented unilateral erythematous
scaly plaques arranged along Blaschko lines in the left hemithorax, with no
associated symptoms and no lesions in other parts of the body. The differentiation of
linear psoriasis from other linear dermatoses is not easy. The combination of a
thorough history, a careful examination of the skin and histopathology are essential
to ensure the correct diagnosis and appropriate treatment.
Chronic cutaneous lupus erythematosus in a linear configuration is rare,
particularly in children, demonstrating similar incidence in both genders, no
photo-sensitivity and lower probability of progression to systemic disease. We
describe the case of a 9-year-old girl who presented erythematous papules with
central atrophy on the upper and lower right limbs, asymptomatic and following
the lines of Blaschko, since age four. Histological examination showed atrophy
of the epidermis with aggression from epidermal-dermal interface and periadnexal
and perivascular lymphocytic inflammatory infiltrate. Laboratory tests showed
ANA in a titer of 1:320, in a dense and fine speckled pattern. Due to the rarity
of presentation and location of the disease, this case is reported here.
This paper describes the association of two unusual side effects of treatment
with isotretinoin for severe acne: paronychia and excess granulation tissue in
the nails furrows. We report a case of male patient aged 19 years, who in the
course of the 36th week of treatment with isotretinoin for acne grade III showed
erythema, edema, excess granulation tissue and onychocryptosis in various nail
beds of hands and feet, with no history of trauma associated. A literature
review revealed few reports of these adverse events, and two clinical patterns
of exuberant granulation tissue has been described: one in periungual location
and other in lesions of previous acne. The rarity and lack of knowledge on the
best treatment for granuloma-like reactions make this theme a considerable
challenge.
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