The electrocardiogram (ECG) is one of the most reliable information sources for assessing cardiovascular health and training success. Since the early 1990s, the heart rate variability (HRV), namely the variation from beat to beat, has become the focus of investigations as it provides insight into the complex interplay of body circulation and the influence of the autonomic nervous system on heartbeats. However, HRV parameters during physical activity are poorly understood, mostly due to the challenging signal processing in the presence of motion artefacts. To derive HRV parameters in time (heart rate (HR)) and frequency domains (high frequency (HF), low frequency (LF)), it is crucial to reliably detect the exact position of the R-peaks. We introduce a full algorithm chain where a sophisticated filtering technique is combined with an enhanced R-peak detection that can cope with motion artefacts in ECG data originating from physical activity
The acquisition of high-resolution retinal fundus images with a large field of view (FOV) is challenging due to technological, physiological and economic reasons. This paper proposes a fully automatic framework to reconstruct retinal images of high spatial resolution and increased FOV from multiple low-resolution images captured with non-mydriatic, mobile and video-capable but low-cost cameras. Within the scope of one examination, we scan different regions on the retina by exploiting eye motion conducted by a patient guidance. Appropriate views for our mosaicing method are selected based on optic disk tracking to trace eye movements. For each view, one superresolved image is reconstructed by fusion of multiple video frames. Finally, all super-resolved views are registered to a common reference using a novel polynomial registration scheme and combined by means of image mosaicing. We evaluated our framework for a mobile and low-cost video fundus camera. In our experiments, we reconstructed retinal images of up to 30• FOV from 10 complementary views of 15• FOV. An evaluation of the mosaics by human experts as well as a quantitative comparison to conventional color fundus images encourage the clinical usability of our framework.
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