Self-poisoning is an important medical and social problem in adolescents.We performed an observational cross-sectional retrospective study on a group of 219 adolescents admitted for voluntary intoxications at “St. Mary” Children's Emergency Hospital, Iasi during 1 year period. Epidemiological aspects and triggering factors have been analyzed. Data collected from the patients’ files were centralized in an SPSS 18.0 database and processed with confidence interval of 95%.We found that pharmaceutical drugs have been usually involved (34.7%), mostly in girls (56.3% vs. 15.5%; P = 0.0001). The most frequently cited reason for poisoning was family conflict, with a relative risk (RR) 1.43 times higher in girls, as well as scholar conflict (RR = 1.39). A great percentage of the monitored girls presented severe depression (23.3% vs. 6.9%; P = 0.001), with an RR more than 3 times higher than in the case of boys. All cases evolved favorably, no death having been recorded, even if 18 teenagers initially presented an extremely serious condition, being admitted in various stages of coma (Glasgow coma scale score < 8).We found that self-inflicted poisonings with pharmaceutical drugs was more common in girls and the use of drug and alcohol intoxication was found especially in boys. The most common pharmaceutical drug involved in self-poisoning was acetaminophen. Psychological disorders and family or school conflicts are the most important triggering factors of voluntary poisoning. Risk factors should be identified after stabilizing the patient, and actions should be taken in order to prevent a fatal recurrence.
Accidental poisonongs are an important cause of morbidity and even mortality, especially in young children.We performed a retrospective observational study on a group of children admitted at the Regional Center of Toxicology at the Children's Emergency Hospital “St. Mary” Iasi with accidental intoxication within a period of 3 years. Data were collected from patients’ files and processed with a SPPS 18.0 database and a 95% confidence interval.During this period, 480 children were admitted with accidental intoxication. Most of them were in the age group of 1 to 2 years (120 cases—24.3%). The etiology of these intoxications was dominated by nonmedication (67%), the most frequent being household chemicals, carbon monoxide, and insecticides. Accidental drug intoxication accounted for 33% of the cases, the main drugs involved being anticonvulsants, nonsteroidal anti-inflammatory drugs, and paracetamol. The mortality caused by accidental poisoning was 0.62%, all deaths owing to nonmedication intoxication.Identifying the epidemiological and evolutionary aspects of accidental intoxications must be a major objective for the health system, given that this pathology can be at least partially avoided and its incidence and severity may be reduced using appropriate measures.
Background and aimsAcute laryngitis is the most common cause of upper airway obstruction in children, accounting for 90% of stridor case. The aim of the study was to evaluate the clinical-epidemiological profile of children with croup.MethodsThe study group consists in 94 children, 37 girls and 57 boys, aged 3 months – 13 years, hospitalised in a Paediatric Clinic during 16 months, diagnosed with acute laringytis. Diagnostic criteria were the presence of inspiratory laryngeal stridor, dysphonia, and barking cough.ResultsThe distribution of patients by age groups showed that 18% were infants, 45% were 1–3 years age old, 24% of patients were 3–7 years age old and 13% of patients were older than 7 years. Depending on the environment, 45% of patients were from urban areas and 55% from rural areas. The incidence of croup was higher in autumn-winter periods, 64% of cases. Anamnesis showed a high risk of croup in patients with previous respiratory infections, 33% of children; also 10% of patients had recurrent laryngitis. Associated symptoms were headache (16% of cases), dysphagia (6% of cases), loss of appetite (21% of cases), nasal obstruction in 50% of patients, runny nose in 31% of patients and ear pain in 16% of patients. Based on Downes score, laryngitis was mild in 32% cases, moderate in 20% cases and severe in 48% cases. Three cases were suspected of epiglottitis and x-ray was performed. Severe cases needed oxygen administration and 51% of them association of antibiotic in treatment.ConclusionsMost of patients in the study group had severe manifestation of laryngitis. The peak incidence was in children aged 1–3 years, predominantly in boys.
Chronic otitis, one of the major causes of pediatric hypoacusia is frequent associated with some allergic diseases. The continuous rice of atopic diseases prevalence in childhood, involves a multidisciplinary approach of Eustachian tube dysfunction, adenoid inflammation or recurrent otitis, for a complex pathogenic management. The objective of this study was to determinate the association between otitis media and the allergic diseases with the implication in the treatment and evolution of this patients. Methods. Retrospective study on 92 children, between 6 month and 6 years, admitted in II Pediatric Clinic, Clinical Hospital of Children “Sf. Maria” Iasi with diagnosis of acute otitis media, for a period of 1 year. Results. Majority of cases (61patients) have been suppurate otitis, 31 cases have been otitis media with effusion out of which 23 have been recurrent. Association with allergic diseases has been more frequent in children with serous otitis media (26/31 cases). 4 cases with suppurate otitis media have developed adverse reaction to antibiotics with major implication in the cases evolution. Association with gastroesophageal reflux was relatively similar between cases with serous otitis and the suppurate ones (10/31 cases and 11/61 cases). From the atopic patients with gastroesophageal reflux, 10 presented cow’s milk protein allergy. In conclusion, the children with otitis media, especially those with recurrent none suppurate form should be investigated for atopy and, eventually, for gastroesophageal reflux, possibly with determination of the allergic markers or of pepsin in the otic exudates, in order to a targeted therapeutic management.
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