The anterior pituitary has been a n object of histological interest for more than fifty years. This interest has been directed largely toward a study of the distinct cell types, two of which, the chromophobes (noii-staining, non-granulated cytoplasm) and the chromophiles (with demonstrable cytoplasmic granules) were described as early as 1884 by Flesch. Schoeneman (18!92) further divided the chromophiles into acidophiles arid cyanophiles (now more frequently known as basophiles), terms which a r e self-descriptive. These two granular types together with the non-granular chromophobes remain today the only well-established cell types of the normal gland. Although the original cytological interest in the anterior pituitary was elicited by its unique embryology, the great impetus for its study during the last decade has come from the realization of the gland's important eiidocrine functions. The present work is the result of renewed demands constantly being made hy rapidly accumulating physiological data for a better cytological interpretation of the pituitary phenomena. Reviews of the literature conceriiing anterior lobe histology can be found in the excellent papers of Kraus ('14) and Bailey ('21) which introduce the reader to a wide literature. The present paper is a more Aided by a grant from the National Rcscwrcli Council, Committee for Rcscarcli in Problems of Sex, administered by Dr. P. 13. Smith.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.