Metabolic syndrome (MetS) and visceral adiposity are crucial cardio metabolic risk factors. There is evidence of subclinical left ventricular myocardial dysfunction in individuals with metabolic syndrome (MetS). However, the effect of MetS on the right ventricle (RV) is yet unknown. By using 2D Speckle Tracking Echocardiography, we investigated the link between MetS and right ventricle function. This study was conducted on 50 MetS patients and 25 age and gender matched individuals (control group). The MetS is diagnosed when presence of ≥3 American Heart Association/National Heart, Lung, and Blood Institute criteria. All individuals had sufficient laboratory assays as well as a thorough 2D examination including tissue Doppler imaging (TDI) and R. V global longitudinal strain (GLS) during the period between November 2019 and December 2020. The metabolic group had a statistically significant lower RV-GLS (-18.27±2.16 in MetS subjects vs. -26.64±3.05 in control subjects, P<0.001), a significantly lower E/A ratio (0.95±0.12 in MetS subjects vs. 1.14±0.15 in controls, P<0.001), and a statistically significant increase in the E/Em ratio (5.66±1.03 in MetS subjects vs. 4.24±0.46 in controls, P<0.001). Other echocardiographic or functional capacity tests revealed no significant differences between the two groups. We concluded that MetS was associated with preclinical right ventricle systolic dysfunction detected by 2D-STE observed with Normal RV by TAPSE and FAC and Normal left ventricular ejection fraction (LVEF) in addition to RV diastolic dysfunction.
Background: Tissue Speckle Tracking examines speckle aberrations in an echo picture to determine myocardial contractility and relaxation. Reflections, refraction, and dispersion of echo beams generate speckles. Aim of the study: The purpose of this research was to use speckled tracking echocardiography to identify subclinical left ventricular failure in young hypertension individuals who had normal systolic function by 2D echocardiography. Patients and Methods: The research included 30 hypertensive patients with preserved ejection fraction referred to cardiology department at AL azhar University hospital for echocardiography assessment and 20 controls. All patients were assessed clinically followed by M-Mode and 2D echocardiography assessment, pulsed wave Doppler mitral inflow as well as offline speckle tracking echocardiography.Result: Demographic data, anthropometric measurements, blood pressure measurements, conventional tissue Doppler, and strain echocardiography were compared between the two groups. Body mass index, systolic and diastolic blood pressure, left ventricular end diastolyic dimension, interventricular septal diameter, posterior wall diameter, relative wall thickness, left ventricular mass index, end diastolic volume, E/, left atrial diameter, aortic diameter, left atrial volume index, normal systolic velocity of tissue doppler mitral inflow, and GLS. The control group had a considerably greater systolic velocity (p=0.013). In comparison to the hypertension group, GLS was considerably greater in the control group (-21.25± 1.18 vs -19.18±1.66, p=0.001).
Conclusion:The final result of the research recommends comprehensive longitudinal stress assessment and tissue Doppler imaging for all newly discovered arterial hypertension patients or patients with arterial hypertension who have normal ejection fraction and suffer from shortness of breath.
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