We report on a 41-year-old woman with refractory systemic lupus erythematosus with massive pericarditis, macrophage activation syndrome, and glomerulonephritis despite high-dose glucocorticoids and tacrolimus. Tocilizumab dramatically improved pericarditis, and glomerulonephritis was controlled after adding cyclophosphamide. We had to halt tocilizumab and cyclophosphamide due to possible pneumocystis infection after five and three infusions of tocilizumab and intravenous cyclophosphamide, respectively. Nevertheless, no lupus flare had been observed on glucocorticoid monotherapy and enabled further rapid tapering prednisolone.
Chemotherapy has shifted from hospital care to ambulatory care. To ensure safe and certain ambulatory chemotherapy, a community pharmacist is expected to feed back information about the medicine-taking situation at home to hospital staff. In this study, we estimated the establishment of a tracing-report system using telephone communication, with the aim of organizing concerted intervention among physicians, hospital pharmacists and community pharmacists. Among the outpatients who were treated S-1 from June 1, 2014 to April 30, 2015, 25 patients agreed to receive an inquiry call at home. Medication compliance and the number of unused medicines were monitored by a community pharmacist and this information was reported to a physician via a hospital pharmacist by using 'The Tracing Report.' The names of diseases were confirmed in 24 patients, and the chemotherapy method was confirmed in 23 patients. Physicians accepted recommendations from pharmacists in 30 out of 47 cases.In conclusion, the results suggest that an inquiry call from a community pharmacist during ambulatory care, verifying their medicine taking situation, contributed to safe chemotherapy.
This paper investigated how words in Japanese and American rap music were represented in terms of two phonological units, morae and syllables. The main question addressed in this study was to find out which unit was preferred to represent words in Japanese and American rap music. One hundred CVN syllables in two or multi-syllable words were identified from 9 pieces of 2 Japanese musical bands and 27 pieces of 3 American musical bands. Then, the first author set these syllables to music one by one, using a Japanese computer music software to determine how these syllables were assigned to notes. The analysis showed that 73% of the CVN syllables in Japanese rap music were assigned to a note which was two times longer than that of the following note and 27% were assigned to two separate equivalent notes, while 93% of the CVN syllables in American rap music were assigned to a single note which was equivalent to the following note. In other words, the computation of duration was considered to choose notes in the former, while it was not in the latter, suggesting that words in Japanese and American rap music were represented in terms of morae and syllables, respectively.
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