Nd-Ca-based manganite Nd0.5Ca0.5MnO3 and 10% Ti-doped manganite Nd0.5Ca0.5Ti0.1Mn0.9O3 denoted by N and N0.1, respectively, were prepared using solid-state reaction method. Resistivity gets increased for the Ti-doped sample. The parent compound N has remarkably high magnetoresistance. The highest value of Seebeck coefficient for N is -97 μVK-1 at 143 K and for N0.1 is -207 μVK-1 at 203 K. Variable range hopping mechanism successfully explains the high temperature resistivity and thermopower data. Keywords: magnetoresistance, thermoelectric power, rare-earth based manganites, manganites.
Phytotherapy is an inevitable companion of human civilization. Smilax wightii is an ethnomedicinal plant in Smilacaceae, with unexplored scientifically therapeutic potential. The antihyperglycemic, antioxidant and hepatoprotective capabilities of the methanolic extract of leaf, stem, rhizome and root of S. wightii were inspected in the present study. Hyperglycemia is a manifestation of the prevalent metabolic disorder, Type 2 Diabetes mellitus. Inhibitors of α –glucosidase and α – amylase could be efficiently employed in diabetes mellitus therapy as hypoglycemic agents. In the α –glucosidase and α – amylase inhibitory assays, root and rhizome extracts recorded better antihyperglycemic activity. DPPH radical scavenging activity and total antioxidant capacity were the parameters employed to determine the antioxidant activity. Hepatoprotectivity determines the capability of samples to safeguard the hepatocytes from damage. Novel hepatoprotective agents are in demand since the incidence of liver impairment is on a high among global population. The rhizome extract showed comparatively superior hepatoprotectivity followed by the leaf, stem and root extracts. Rhizome, at 100μg/ml guaranteed a cell viability percentage of 77.43 in the Chang liver cell line treated with Carbon tetrachloride. So the root and rhizome of S. wightii are the therapeutically significant plant parts with hypoglycemic, free radical scavenging and hepatoprotective potentialities.
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