IntroductionAlthough chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) predominantly affects large myelinated fibers, many patients have pain. The aim of this paper is to systematically review the current literature regarding CIDP with a particular focus on epidemiological and clinical characteristics of painful CIDP.MethodsA systematic literature search was conducted on PubMed database.ResultsOur search strategy identified 146 articles. Thirty-eight papers, reporting on 991 patients, met the inclusion criteria and were used for this review. The pooled estimate of the prevalence of pain at any point within the course of CIDP was 46% (95% CI 36–57%). Immune treatment of CIDP might be adequate as monotherapy for the management of pain. Treatment specific to pain currently shows effectiveness as adjuvant treatment when CIDP is treated and pain persists.ConclusionsPain in CIDP is an underexplored field. Future research should focus on the natural history, phenomenology, and management of pain in CIDP.
Background: Vasectomy is one of the permanent methods of contraception; however, the risk of conception still exists. Early failure, defined as a postoperative semen analysis showing persistent motile sperm, occurs in 1 in every 250 patients. Late failure, defined as the rejoining of the severed ends of the vas deferens, occurs in 1 in every 2000 patients. Case presentation: A healthy 37-year-old British male presented to our clinic because his wife had conceived seven years after he had undergone a vasectomy. The result of his semen analysis after the vasectomy was negative, and the histopathological report confirmed that the sample contained tissue from both the left and right vas deferens. His wife conceived seven years after the procedure, and semen analysis at that time confirmed a total of 0.5 million sperm per milliliter of semen in a total semen sample of 6.3 ml. The total number of motile sperm recorded was 2.5 million. Conclusion: This case shows that late recanalization can occur up to seven years after a vasectomy. Patients should be informed prior to the procedure that late recanalization, although rare, may still occur. Post-vasectomy paternity necessitates further counseling to ensure that the patient and the patient's partner fully understand the implications and options available to them.
Background: To assess how ready current FY1 doctors felt when starting their first posting as newly qualified doctors. Methods: We created an online survey where 45 FY1 doctors in South Yorkshire rated how confident they were across different domains (Induction and Assistantship, Hospital Systems, and Skills) using a scale ranging from 0 (no confidence performing task) to 5 (highly confident). Results: The ICE system and observations had a mean rating of 3.645 (95% CI 3.446 to 3.844), and 4.425 (95% CI 4.248 to 4.602) with a standard deviation (SD) of 1.10 and 0.83 respectively. The radiological platform, referral system, telephone system, and hospital notes had a mean score of 3.149 (95% CI 2.876 to 3.422), 2.340 (95% CI 2.096 to 2.584), 3.573 (95% CI 3.407 to 3.739) and 4.061 (95% CI 3.931 to 4.191), with a SD of 1.281, 1.153, 0.961 and 0.752 respectively. Patient needs and diagnostic procedures had a mean score of 3.933 (95% CI 3.749 to 4.117) and 4.250 (95% CI 4.140 to 4.360) with a SD of 1.190 and 0.944 respectively. Patient care, prescribing, and therapeutic procedures gave a mean score of 3.634 (95% CI 3.432 to 3.836), 4.130 (95% CI 3.959 to 4.301), 3.386 (95% CI 3.228 to 3.544) with a SD of 1.133, 0.958 and 1.256 respectively. No statistically significant difference in the overall mean score was found between respondents who attended medical schools in Yorkshire, and those who had not. Conclusion: Overall, confidence differs across different domains and categories. A larger sample size across a wider geographical area would allow us to compare and contrast results across the different regions in the UK.
Background: To assess how ready current FY1 doctors felt when they started their first posting as newly qualified doctors. Methods: We created an online survey where 45 FY1 doctors in South Yorkshire rated how confident they were across different domains (induction and assistantship, hospital systems, and skills) using a scale ranging from 0 (no confidence in performing task) to 5 (highly confident in performing task). Results: Responses showed that the ICE system and observations had a mean rating of 3.645 (95% CI 3.45 to 3.86), 4.425 (95% CI 4.25 to 4.6) with a standard deviation (SD) of 1.1 and 0.83 respectively. The radiological viewing platform, referral system, telephone system, and hospital notes had a mean score of 3.149 (95% CI 2.88 to 3.42), 2.341 (95% CI 2.1 to 2.58), 3.573 (95% CI 3.41 to 3.74) and 4.061 (95% CI 3.93 to 4.19), with a SD of 1.281, 1.154, 0.961 and 0.752 respectively. FY1’s wanted more training on referrals [(84.09%(n=37)) and use of phones [43.2% (n=19)]. Vital observations and diagnostic procedures scored a mean score of 3.933 (95% CI 3.75 to 4.12) and 4.251 (95% CI 4.14 to 4.36) with a SD of 1.19 and 0.944 respectively. The patient care category, the prescribing category and therapeutic procedures gave a mean score of 3.634 (95% CI 3.44 to 3.83), 4.13 (95% CI 3.96 to 4.3), 3.386 (95% CI 3.23 to 3.54) and an SD of 1.128, 0.954 and 1.253 respectively.Conclusion: Overall, junior doctors are confident in most tasks and jobs expected of them. A greater sample size would enable us to compare how different medical schools and deaneries aid this transition.
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