The overall risk of hip fracture among Caucasian patients with ESRD is considerably higher than in the general population, independent of age and gender.
Demographic and other characteristics that predict risk of hip fracture in the population at large also do so in ESRD patients. However, we could identify no characteristics of ESRD or its treatment that were independently related to hip fracture incidence.
Risk factors for hip fracture among patients with end-stage end-stage renal disease (ESRD). ESRD patients, howrenal disease. ever, are 4.4-fold more likely to sustain a hip fracture Background. Although bone disease is well described among than the general population [2]. The relative risk (RR) end-stage renal disease (ESRD) patients, little attention has of hip fracture among ESRD patients varies by age and been paid to the occurrence of fracture. We sought to identify gender and ranges from a 99-fold higher risk among men factors that are associated with hip fracture among ESRD patients. younger than 45 years to a 1.7-fold increased risk among Methods. Data from patients who participated in the United women older than 85 years. Risk factors for hip fracture States Renal Data System Dialysis Morbidity and Mortality in the general population have been well described and Study Wave 1 were used for this study. Hip fractures occurring include bone loss, increasing age, Caucasian race, smokamong these patients between 1993 and 1996 were identified ing, female gender, and lower body weight [3-7]. Several from Medicare claims data available from the United States Renal Data System. Cox proportional hazards models were investigators have demonstrated low bone mineral denused to estimate the risk of hip fracture associated with demosity among ESRD patients [8-11] and have identified renal graphic and medical variables. osteodystrophy, ethnicity, age, transplantation, and amen-Results. Of the 4952 patients included in this analysis, 103 orrhea as factors contributing to bone loss. Low bone sustained a hip fracture. In the multivariate analysis, age (per increasing decade, RR ϭ 1.40, 95% CI 1.20, 1.64), female
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