CADRs were more common in women and most of them were caused by antimicrobial agents followed by NSAIDs and anticonvulsants. Latency period of anticonvulsants were longer than the other groups.
Hypohidrotic ectodermal dysplasia (HED; Christ-Siemens-Touraine syndrome) is a genetic disorder characterized by sparse hair, oligodontia with peg-shaped teeth, reduced sweating, and defects in a number of other ectodermal organs. A partial or complete absence of eccrine glands can lead to recurrent severe overheating that may cause seizures and neurological deficits. This clinical report presents a 14-year-old male patient with hypohidrotic ectodermal dysplasia, including the clinical and radiographic findings, and multidisciplinary treatment. The Schedule for Affective Disorders and Schizophrenia for School Aged Children-Present and Lifetime Version (K-SADS-PL) was administered to patient along with mother to assess for any psychiatric disorders. The screening and rating scales completed by mother and two teachers to evaluate the severity of attention deficit hyperactivity disorder (ADHD) symptoms, and other behavioral problems. Patient's academic performance, adaptive functioning, and problem behavior was evaluated using. The Teacher Report Form. Mental capacity was assessed with the Wechsler Intelligence Scale for Children (WISC-R). Illness Perception Questionnaire Revised was used to systematically assess illness representation attributes and emotional representations of illness. On the psychiatric diagnosis assessment using K-SADS-PL sub-threshold attention deficits and anxiety symptoms were determined. In this case we established a multidisciplinary approach in his treatment with pediatric, dermatological, and dental examinations, beside his psychiatric evaluation. The prosthetic rehabilitation included restoring upper teeth with copings and fabrication of upper and lower complete dentures. Metal framework was not incorporated in the partial denture design allowing modifications as the oral and maxillofacial development continued. Removable complete or partial dentures without metal framework is a treatment of choice until the completion of facial growth at which definitive treatment is considered.
Background and Design:Psoriasis is a chronic, inflammatory disease that occurs with polygenic and other triggering factors. The association of psoriasis, which is considered to be a systemic disease, with other diseases, such as cardiovascular diseases, hepatosteatosis, obesity, diabetes mellitus, hypertension, and hyperlipidemia has been shown. Materials and Methods:In this study, we compared the levels of fasting blood glucose, serum lipid (total cholesterol, HDL cholesterol, triglyceride), basal insulin, insulin resistance and body mass index as well as cigarette and alcohol consumption in 50 adult patients with those in 50 age-and gender-matched non-psoriatic controls. Results: In our study, metabolic syndrome was present in 62% patients with psoriasis, compared with 24% of the controls (p<0,001). In psoriatic patients with metabolic syndrome PASI median value was 13,6, whereas patients without metabolic syndrome PASI median value was 11,2 and the difference was statistically significant (p<0,001). Conclusion: In our study, the frequency of metabolic syndrome and its components diabetes mellitus, obesity, hypertension, and dyslipidemia were found to be higher in patients with psoriasis compared to that in non-psoriatic controls. (Turkderm 2014; 48: 95-9)
Türk derm-De ri Has ta lık la rı ve Fren gi Ar şi vi Der gi si, Ga le nos Ya yı ne vi ta ra f›n dan ba s›l m›fl t›r. Turk derm-Arc hi ves of the Tur kish Der ma to logy and Ve ne ro logy, pub lis hed by Ga le nos Pub lis hing. ÖzetVulvar sikatrisyel pemfigoid, büllöz pemfigoidin çocukluk çağında görülen, izole ve lokalize vulvar tutulumla karakterize nadir bir varyantıdır. Sum maryVulvar cicatricial pemphigoid is a rare variant of bullous pemphigoid, which is characterized by isolated and localized vulvar involvement, observed in childhood. The typical clinical finding is erosive lesions of the vulva healing with scar formation. Ocular involvement may be associated with vulvar disease or may develop during the follow-up. On histopathologic examination of the lesions, subepidermal blister and on direct immunofluorescence study, linear deposition of Ig G and C3 are observed. The differential diagnosis includes lichen sclerosus and, sexual abuse should be considered at first. Topical and systemic steroids and dapsone are the main treatment options. Ophthalmological examination and follow-up should be repeated on every six months for ocular involvement. Here, we report development of vulvar cicatricial pemphigoid in an 11-year-old girl with clinical and histopathological findings. (Turkderm 2014; 48: 51-3)
Amaç: Kemik iliği transplantasyonu (KİT), pediyatrik hastalarda birçok malign ve malign olmayan hastalıkta kullanılmaktadır. Transplantasyon yapılan hastalarda gözlenen deri belirtileri, genellikle altta yatan primer hastalığa ya da uygulanan yoğun kemoterapi ve radyoterapi protokollerine bağlı olarak ortaya çıkmaktadır. Bu çalışmada, KİT yapılan pediyatrik olgularda mukokutanöz lezyonların tanımlanması amaçlanmıştır. Gereç ve Yöntem: Çalışmaya 2010-2011 yılları arasında KİT yapılması planlanan toplam 44 hasta dahil edilmiştir. Olguların ilk dermatolojik muayeneleri yapıldıktan sonra ilk ay içerisinde her hafta, takip eden 5 aylık süreçte ayda bir ve son 1,5 yılda ise her 3 ayda bir dermatolojik muayeneleri tekrarlanmıştır. Bulgular: Kırk bir olgu çalışmayı tamamladı. Toplam 41 olgunun yaş ortalaması 9,24 (minimum=1 yaş, maksimum=17 yaş); hastaların 26'sı (%64) erkek, 15'i (%36) kadındır. Görülme sıklığı oranlarına göre dermatolojik belirtiler mukozit (%75,6), kseroderma (%70,7), alopesi (%46,3), aftöz stomatit (%22), kutanöz hiperpigmentasyon (%22), tırnak bozuklukları (%24,3), enflamatuvar deri hastalıkları (%24,2), enfeksiyöz hastalıklar (%15,5), graft versus host hastalığı (%17,1) ve makülopapüler döküntü (%4,8) şeklinde sıralanmıştır. Sonuç: KİT hastalarında dermatolojik hastalıklar sıklıkla görülebilmektedir. Dermatolojik belirtilerin yakın takibi bu hasta grubunda tedavinin komplikasyonlarını azaltmada önemlidir. Anahtar Kelimeler: Çocuk, deri, kemik iliği transplantasyonu Background and Design: Bone marrow transplantation (BMT) is performed for many malign and non-malign diseases in pediatric patients. Cutaneous signs in transplant patients are usually encountered in the presence of underlying primary diseases or due to the intense conditioning regimens that include chemotherapy and radiotherapy protocols. In this study, it is aimed to define mucocutaneous changes in pediatric patients with BMT. Materials and Methods: A total of 44 patients, in whom BMT was planned between 2010 and 2011, were included in the study. Dermatological examinations were performed at the beginning of the study and were repeated once a week in the first month, once a month in the following 5 months; and once in every 3 months in the last 1.5 years of follow-up. Results: Forty-one patients were completed the study. The mean age of 41 patients was 9.24 years (range: 1-17 years). Of the subjects, 26 (64%) were male and 15 (36%) were female. Dermatological signs, in order of frequency, were mucositis (75.6%), xeroderma (70.7%), alopecia (46.3%), nail disorders (24.3%), inflammatory skin diseases (24.2%), aphthous stomatitis (22%), cutaneous hyperpigmentation (22%), graft versus host diseases (17.1%), infectious diseases (15.5%), and maculopapular rash (4.8%). Conclusion: Dermatological diseases can be frequently observed in BMT patients. Close monitoring of dermatological signs is important to minimize the complications of the treatment in this patient group.
Background and Design: Tinea corporis, a cutaneous infection of the glabrous skin, excluding palms-soles, nails and groins, is caused by dermatophytes.The distribution of agents varies depending on geographical and socio-economic factors. In this study, we aimed to analyze the agents seen in tinea corporis and their relationship with patient age, gender and lesion location. Materials and Methods: In this study, we retrospectively analyzed mycological examination results of 62 patients (62.9% female, 37.1% male) who attended our dermatology outpatient clinic and were diagnosed with tinea corporis between January 2007 and December 2011. The results were compared in terms of patient age, sex and location of lesions for the statistical significance. Results: The average age of the patients was 40.5 years. Trichophyton rubrum was the most prevalent etiologic organism in both gender (56.5%), followed by Microsporum canis (35.5%), Trichophyton violaceum (4.8%) and Trichophyton mentagrophytes (3.2%). The prevalence of Microsporum canis was 46.5% in women and 17.3% in men; the difference was attributed to the fact that women have more close contact with pets, which are an important source of contamination for The zoophilic dermatophyte Microsporum canis, than do men. Conclusion: In our study, the frequency and the species of tinea corporis were found to be similar to that in the literature. There was no statistically significant difference between the variables of agent species, localization, gender and age. However, epidemiological data can be important in the management of the disease in conditions that mycological culture cannot be considered. (Turkderm 2014; 48: 71-3)
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