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The nine FDA-approved protein biomarkers for the diagnosis and management of cancer are approaching maturity, but their different glycosylation compositions relevant to early diagnosis still remain practically unexplored at the sub-glycoproteome scale. Lectins generally exhibit strong binding to specific sub-glycoproteome components and this property has been quite poorly addressed as the basis for the early diagnosis methods. Here, we discuss some glycoproteome issues that make tackling the glycoproteome particularly challenging in the cancer biomarkers field and include a brief view for next generation technologies.

Abstract-Intrusion Detection System (IDS) is an importantand necessary component in ensuring network security and protecting network resources and infrastructures. In this paper, we effectively introduced intrusion detection system by using Principal Component Analysis (PCA) with Support Vector Machines (SVMs) as an approach to select the optimum feature subset. We verify the effectiveness and the feasibility of the proposed IDS system by several experiments on NSL-KDD dataset. A reduction process has been used to reduce the number of features in order to decrease the complexity of the system. The experimental results show that the proposed system is able to speed up the process of intrusion detection and to minimize the memory space and CPU time cost.

Plant diseases compose a great threat to global food security. However, the rapid identification of plant diseases remains challenging and time-consuming. It requires experts to accurately identify if the plant is healthy or not and identify the type of infection. Deep learning techniques have recently been used to identify and diagnose diseased plants from digital images to help automate plant disease diagnosis and help non-experts identify diseased plants. In this paper, an end-to-end deep learning model is developed to identify healthy and unhealthy corn plant leaves while taking into consideration the number of parameters of the model. The proposed model utilizes two pre-trained convolutional neural networks (CNNs), EfficientNetB0, and DenseNet121, to extract deep features from the corn plant images.The deep features extracted from each CNN are then fused using the concatenation technique to produce a more complex feature set from which the model can learn better about the dataset. In this paper, data augmentation techniques were used to add variations to the images in the dataset used to train the model, increasing the variety and number of the images and enabling the model to learn more complex cases of the data. The obtained result of this work is compared with other pre-trained CNN models, namely ResNet152 and InceptionV3, which have a larger number of parameters than the proposed model and require more processing power. The proposed model is able to achieve a classification accuracy of 98.56% which shows the superiority of the proposed model over ResNet152 and InceptionV3 that achieved a classification accuracy of 98.37% and 96.26% respectively.INDEX TERMS Colutional neural networks, deep learning, deep features, feature fusion, plant disease.

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