BACKGROUNDRetinoblastoma is the commonest childhood primary malignant intraocular neoplasm that is often characterised by spontaneous regression. They display photoreceptor differentiation. This study provides the clinical presentations and histological profiles of retinoblastoma in a tertiary care centre in Chhattisgarh State, in Central India. MATERIALS AND METHODSA retrospective study of clinically and histologically verified retinoblastoma at Pt JNM Medical College, Raipur, Chhattisgarh from January 2010 to December 2011 was undertaken. The clinical and histological features were analysed using the patient's case folder and surgical pathology records. RESULTSThere were 50 patients, 32 males and 18 females (M:F ratio 1.7:1), age range from 5½ months to 6 years with 42 eyeball tumours histologically confirmed retinoblastoma during the study period. Proptosis with chemosis was the most common clinical presentation (76.1%). Bilaterality was 15% in this study. Enucleation and Exenteration combined with chemotherapy were offered to 31 (75%) and 11(25%) patients respectively. CONCLUSIONModerately differentiated type with extensive areas of tumour necrosis was the commonest histological pattern. 27 (65%) of the patients died before completing the course of chemotherapy.
In the press moulding process, the challenging task is to increase the productivity cycle of the product with zero rejection. Major problems involved in this process are the consumption of time and deduction of temperature for the loading and unloading process of the material in the mould plate. It is recommended to preheat the mould plate to a certain limit so that the temperature needed while processing is obtained in a shorter span of time. To overcome the time consumption problem, the mould plate should be mounted in a shorter interval of time todecrease the raw material loading time process. In this case, it helps to uplift the productiveness and leads us to a zero rejection rate
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