Abstract:Introduction: Growing teratoma syndrome (GTS), first described in 1982, presents as newly growing metastatic masses in patients previously treated for immature teratoma. Since 1994, only 13 cases have been reported in India. Case Report: A 21 year old male who had undergone orchidectomy for immature teratoma presented with retroperitoneal mass 6 months later. He received 4 cycles bleomycin-etoposide-cisplatin based chemotherapy without change in size of mass. He underwent excision of tumor and retroperitoneal lymph nodes. Histopathology revealed mature teratoma predominantly cartilage, respiratory and enteric epithelium and adipose tissue without immature elements. Conclusion: These tumors cause adjacent vascular and organ invasion causing compressive symptoms. GTS mimics tumor recurrence and patients need to be on regular follow up for detecting these tumors, for they are resistant to chemoradiotherapy and are amenable to surgical resection.
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