Sinonasal neoplasia metastasizing to distant organs is rare in horses. This case report describes the clinical and imaging findings of a horse with sinonasal neoplasia, which had metastasized to the lung, liver, and humerus. Additionally, the prevalence of sinonasal neoplasia and their incidence of distant metastasis among horses that presented to the Oregon State University Veterinary Teaching Hospital (OSU-VTH) were estimated. Of 5,558 equine patients who presented to the OSU-VTH in the last nine years, 1.4% were diagnosed with sinonasal disease and 10.3% of these cases had sinonasal neoplasia with only one having confirmed distant metastasis. This case was an eleven-year-old quarter horse which was evaluated due to a history of a right forelimb lameness of three weeks duration. Two and a half months later he presented again, this time for unilateral epistaxis and persistent right forelimb lameness. Radiography of the right elbow noted an increasingly irregular, periosteal response and osteolytic lesion of the right distal humeral condyle. At the time of the second presentation, nasosinal endoscopy identified a lobulated mass in the region of the ethmoid turbinates. Histopathology of this mass revealed an adenocarcinoma of nasal origin with metastasis to the lung, liver, and right humerus.
Computed tomography (CT) imaging of the head in equine patients is now commonly performed as CT scanners are more readily available. Head CT has proven valuable in evaluating spatially complex anatomic structures, where radiographic superimposition, or restricted access via endoscopy or ultrasound, limit complete evaluation of the disease process. Head CT has been demonstrated to be incredibly valuable in the evaluation of dental and paranasal sinus disease, disease of the hyoid apparatus and ear, and in evaluation of skull trauma. CT is an excellent modality for assessment of both osseous and soft tissue structures; however, evaluation of complex vascular anatomy and determination of tissue viability is limited without the use of contrast agents. Therefore, various contrast agent protocols including intravenous and intraarterial iodinated contrast administration techniques have been established. CT also has limitations in the evaluation of brain and spinal cord disease, for which magnetic resonance imaging (MRI) has major advantages. Head CT images are most commonly evaluated in transverse planes. However, standard multiplanar reconstructions of the head including dorsal and parasagittal planes improve the understanding of spatially complex disease processes. These reconstructions can be crucial for accurate identification of diseased teeth and determination of the extent and severity of osseous and paranasal sinus disease. Head CT examinations are becoming an increasingly important diagnostic tool in the evaluation of horses with head disorders, and CT imaging findings are an important aspect in the clinical decision-making process. The following review discusses the indications, benefits, and technical considerations for the use of computed tomography (CT) in evaluating non-neurologic head pathologies in equine patients.
A 12‐year‐old female African Clawed Frog (Xenopus laevis) displayed lethargy and anorexia for 1 week. Radiographs detected a moderately reduced volume of aerated lung with lobulated margins with the left lung predominantly affected. Transcelomic ultrasound revealed marked consolidation of the left lung. Postmortem examination confirmed suppurative and histiocytic pneumonia, worse in the left lung, caused by Mycobacterium chelonae. Given that amphibian pulmonary consolidation and celomic effusion can have similar radiographic findings, ultrasound may be helpful to differentiate.
Objective: To determine the location of the deep and superficial caudal epigastric arteries in relation to 3 midline positions and the relationship between the location of these arteries, body circumference, and body condition score. Study design: Descriptive anatomical study. Sample population: Nine horses, aged 1-28 years (mean 10.61 ± 8.89 SD). Methods: Body condition score and body circumference were measured prior to euthanasia. Angiographic studies of the deep and superficial caudal epigastric arteries were performed on resected abdominal walls. The distances between the deep and the superficial caudal epigastric arteries and 3 midline positions were measured. Correlations among these distances, body circumference, and body condition score were analyzed. Results: The location of the deep caudal epigastric artery correlated with body circumference and body condition score at the umbilicus (r = 0.53 and 0.68, respectively), midpoint landmark (r = 0.79 and 0.83, respectively), and prepubic tendon attachment (r = 0.69 and 0.78, respectively). The course of this artery could be estimated by multiplying body circumference by 0.04 ± 0.02 at the umbilicus, 0.07 ± 0.01 at the midpoint landmark, and 0.03 ± 0.015 at the prepubic tendon attachment. The course of the superficial caudal epigastric artery did not correlate with anatomic landmarks. Conclusion: The course of the deep caudal epigastric artery could be estimated at 3 midline landmarks on the basis of body circumference and body condition score in equine cadavers. Clinical significance: Predicting the course of the caudal epigastric arteries in the equine abdomen based on correlation among location, body circumference, and body condition score may prevent iatrogenic damage during creation of laparoscopic portals.
Case summary A stray female domestic shorthair cat was presented to the emergency service after being hit by a car. The patient was recumbent and vocalizing, with a small wound over the right lateral thorax, and two palpably firm swellings in the right cervical and thoracic soft tissues. The patient was sedated and humanely euthanized to prevent further pain and suffering. Post-mortem whole-body radiographs and subsequent necropsy revealed abdominal wall rupture with herniation of two near-term fetuses within the subcutaneous tissues along the right ventrolateral thoracic wall and neck. Within the abdomen, the right uterine horn was ruptured and a third extra-luminal fetus was identified. The left uterine horn remained intact, containing a fourth fetus. Relevance and novel information Rupture of the abdominal wall or diaphragm are well-known potential complications of blunt force trauma, such as motor vehicle accidents. While traumatic uterine rupture and diaphragmatic herniation of the gravid uterus have both been reported in the veterinary literature, abdominal wall rupture with subcutaneous fetal herniation is highly uncommon.
Summary. A 9-year-old 35.6 kg (90 lb) female neutered German Shepherd dog was admitted due to progression of tetraparesis. The dog presented pyrexia, mild leukocytosis, and nonambulatory tetraparesis with decreased general proprioception and withdrawal in all the limbs, with the front limbs more severely affected. Magnetic resonance imaging revealed T2-weighted image (WI) hyperintense, contrast-enhancing lesion at the level of the C6-C8 spinal nerves, and epidural fat, suspected to be an infiltrative neoplasm. Medical treatments during hospitalization included glucocorticoids, antibiotics, and supportive care. Euthanasia was elected 4 days later due to financial constraints, despite clinical improvement. Postmortem findings revealed septic emboli (SE) in the epidural fat exiting the canal and following the tract of the spinal nerve roots and nerves. Staphylococcus pseudintermedius was identified as the causative agent. Although the incidence of SE without severe systemic disease is considered low in dogs, it should be considered in the differential diagnosis of focal intraspinal disease.
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