Objectives: So far, there is no concrete consensus on using uterine Doppler measurements for predicting the adverse outcomes in the early stages of pregnancy between 6-14 weeks. Hence, the current study was planned to investigate the role of uterine artery Doppler in predicting the miscarriage in early pregnancy and to evaluate whether uterine artery Doppler indices abnormality is associated with a complicated pregnancy and adverse outcomes. Materials and Methods: The present cross-sectional prospective study estimated the uterine artery Doppler of right and left uterine arteries and the mean of pulsatility index (PI), resistance index (RI), and systolic/diastolic (SD) ratio was obtained for each patient. The gestational age, at which the Doppler study was performed, was 6-14 weeks for all groups. Finally, the groups of normal and threatened miscarriage were followed up for the outcome up to 20 weeks of gestation. Results: There was a significant difference in the means of PI, RI, and S/D ratio among the three groups. However, PI was the only parameter which was significantly associated with the outcome of pregnancy. In addition, the cut-off value for PI was 2.64 at 91% sensitivity and 81% specificity for predicting miscarriage. Conclusions: In general, uterine artery Doppler should be introduced as the routine screening test for identifying the women who could have an adverse pregnancy outcome for its effective management.

Human papillomavirus (HPV) is a widely prevalent sexually transmitted virus. Although the majority of infections are benign and transient, persistent infection is associated with the development of cervical, vulvar, vaginal and anal cancers (1) .The genital HPV types are divided into two categories, 'high risk' and 'low risk', originally assigned based on whether the HPV type could or could not be found as a solitary isolate in cervical cancer specimens (2) . It is now universally accepted that nearly all the invasive cervical cancers and high grade intraepithelial neoplasia and

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This study was designed to evaluate maternal and obstetrical factors associated with a successful trial of labour after one caesarean section (TOLAC) as well as evaluating the associated fetal and maternal outcomes and to determine the rate of vaginal delivery and repeated C/S. A prospective cross-sectional study was done on 237 women with previous one C/S then patients were selected for the trial of labour based on the department protocol. Those who were chosen for TOL were strictly monitored & observed for the progress of labour and the outcomes were recorded in terms of mode of delivery, maternal & fetal complications and were analysed and compared with those who had repeated C/S. Seventy-three (30.8%) patient was delivered by elective C/S without trial, 109 (46%) of the patients who were admitted to labour room delivered vaginally while 55 (23.2%) delivered by emergency C/S. It has been found that maternal BMI of (<25), history of vaginal birth after C/S (VBAC) and smaller gestational age were significantly associated with the success of TOL and can predict the outcome. Higher maternal & fetal complications rates were reported in cases delivered by emergency C/S compared to those who delivered vaginally or through elective C/S. The trial of labour after one caesarean section is a safe alternative to repeated C/S and decreases the associated morbidities with repeated C/S. The success rate of TOLAC reported in this study was (66.5%). A successful TOLAC is associated with normal maternal BMI, smaller gestational age and history of the previous VBAC.