The production of safflower (Carthamus tinctorius L.) (Asterales: Asteraceae), which is cultivated worldwide, is significantly affected by different abiotic and biotic factors such as insects. Different insecticides have been applied during safflower production to control pests. The application of insecticides can affect plants as well as pests. This study was carried out in Ankara and Eskisehir provinces in 2016 using four different insecticides against the Bangasternus planifrons (Brulle, 1882) (Coleoptera: Curculionidae) pest in Balcı safflower variety. The pest population was 73-91% effectively suppressed as of the 14th day after the application of insecticides, and the yield increased by 60.43-123.18% when compared to the control group. Deterioration of seed quality, loss of oil ratio, and loss of 1000 grain weight occurred as a result of damage occurred by pest feeding. Through control of pests and reduction of pest population, an increase in quality and productivity was achieved. Regression analysis made on the data obtained from the application areas determined that there were 83.73%, 75.83%, and 75.44% negative relationship between the number of adults of the pest and the yield, oil rate, and 1000-grain weight, respectively. In conclusion, B. planifrons is an important factor causing a loss in yield, oil rate, and loss of 1000-grain weight in safflower plant. The damage caused by the pest can be prevented by the application of a suitable insecticide.