Pulsed radiofrequency technique application to the suprascapular nerve for 480 seconds shows remarkable improvement at patients' chronic shoulder pain.
The results of this study indicated that ozone therapy accelerates the healing process, increases vascularity, and reduces neuronal damage in rodents, suggesting that ozone therapy may be an adjuvant treatment in patients with SCI.
BACKGROUND: In the literature, many beneficial effects are attributed ozone; it balances the oxidant-antioxidant system, leads to delivery of super enriched oxygen at a cellular level and optimizes cell function, etc.
PURPOSE: The aim of this study was to evaluate if there is a positive impact of ozone therapy on bone healing in an experimental fracture model in rats.
MATERIAL and METHODS: After approval of experimental animal ethic committee, an open femoral fracture (ffx) was performed in 48 male Spraque Dawley rats. They were randomly divided into two groups: in Group O, medical ozone/oxygen mixture (500 mg/kg) and in Group C, medical air in volume of 4 mL were given rectally for 3-days. At days 4, 7 and 13, eight rats from each group were euthanized, and histomorphometric and immunohistochemical bone tissue evaluation was undertaken from the femur sampling.
RESULTS: Histomorphometrically, periost thickness was thicker, trabecular areas were larger, cartilaginous and new bone areas were smaller (p
AIm: Aim of this study is to assess effects of parenteral nutritional support with fish-oil emulsion on spinal cord recovery in rats with traumatic spinal cord injury. mAterIAl and methOds: For 5 days after SCI rats were received saline in group C and Omegaven in group O. Locomotor strengths (BBB scale)of animals were rated at Day 0,7,14,21,28, and 35. At Day 35 spinal cord sampling was evaluated immunohistochemically.results: BBB scores were 0 in early period after SCI was inflicted in both groups. BBB scores were progressively increased after Day 7 in both groups (p<.005). BBB scores were significantly higher in group O when compared with control group after Day7 in all times (p<.005). Neuronal injury (p<.002) and edema was much more in control group when compared with in group O (p<.005). Scores for white mater cavitation, demyelinization and vessel in growth were similar in both groups. VEGF expression in control group was higher (p=.019).COnClusIOn: At the early period of SCI fish-oil emulsion treatment in rats, its anti-inflammatory effects leaded to decrease in edema and had positive effect at the prevention of neuronal injury. We believe that nutritional support with fish-oil emulsion in patients with SCI will result in patient's better clinical outcome and increase in quality of the patient's life.KeywOrds: Omega-3 fatty acids, Omega-6 fatty acids, Neuron recovery, Nutrition, Spinal cord injury ÖZ AmAÇ: Travmatik omurilik yaralanması olan sıçanlarda omegaven ile beslenme desteğinin iyileşme üzerine etkilerinin araştırılmasıdır. yÖntem ve GereÇ: Omurilik hasarını takiben 5 gün boyunca sıçanlara IP 1mL/kg omegaven veya 0.9NaCl verildi. Lokomotor kuvvet (BBB skoru)0,7,14,21,28 ve 35.günlerde kaydedildi. Otuzbeşinci günde omurilikte histopatolojik inceleme yapıldı.BulGulAr: Kontrol grubunda BBB skorları düşük (p<.005), nöronal hasarlanma (p<.002) ve ödem (p<.005) yüksek bulundu. Beyaz maddede kavitasyon, demiyelinizasyon ve damarlanma skorlarında fark saptanmadı. VEGF kontrol grubunda yüksek bulundu(p=.019).sOnuÇ: Erken dönemde omurilik hasarında balık yağı emulsiyonu ile beslenme desteğinin antiinflamatuar etki ile ödemi azalttığı ve nöronal hasar üzerine koruyucu etkisi olduğu görüldü. Omurilik yaralanması olan hastalarda balık yağı emulsiyonu ile beslenme desteği daha iyi klinik sonuçlar ve daha yüksek yaşam kalitesi sağlayabilir.
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