Fibrodysplasia ossificans progressiva (FOP) is a rare debilitating inherited disorder which is characterized by great toe malformation and progressive heterotopic ossification of connective tissue in which tendons and ligaments are gradually replaced by bone. The extraskeletal heterotopic bone limits the patient’s mobility. The average age of onset is the first 2 decades of life with the current prevalence rate of 1 in 2 million cases worldwide. Thorough clinical examination, characteristic radiological findings, and genetic analysis pave a way in making an early diagnosis for better care and management of the patient with FOP.
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