Background: Laryngeal and hypopharyngeal cancers are commonly diagnosed by histopathological examination of a punch biopsy specimen from the lesion. The histopathological report of the punch biopsy specimen in certain cases is inconclusive, most commonly in cases of endophytic growths. Objective: To evaluate the efficacy of trucut biopsy as a diagnostic procedure in such cases of laryngeal and hypopharyngeal growth which are clinically malignant but histopathology report by punch biopsy is inconclusive. Materials and Methods: Seven cases with clinical suspicion of laryngeal or hypopharyngeal malignancies but with inconclusive histopathological examination on punch biopsy were included. Trucut biopsy was performed in them. 6 out of the 7 trucut biopsies were found to be malignancies on histopathological examination. Conclusion: Trucut biopsy is promising diagnostic tool in laryngeal and hypopharyngeal malignancies especially in those cases where there is strong suspicion of malignancy and the punch biopsy does is inconclusive.
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